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anti-GAD65 antibody :: Rabbit anti-Human GAD65 Polyclonal Antibody

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Catalog # MBS855593
Unit / Price
  0.1 mg  /  $330 +1 FREE 8GB USB
Testing Data
Product Name

GAD65, Polyclonal Antibody

Popular Item
Full Product Name

GAD65 Antibody

Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
OMIM
138275
3D Structure
ModBase 3D Structure for Q05329
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human
Form/Format
Purified by peptide affinity column containing 1% BSA and 0.02% NaN3
Preparation and Storage
Already reconstituted in 200ul sterile H2O. The antibody is stable for at least one year when stored at-20 degree C.
Other Notes
Small volumes of anti-GAD65 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-GAD65 antibody
Rabbit polyclonal GAD65 (1) antibody was raised against a 15 amino acid peptide from near the N terminal residues of human GAD65 protein.
Applications Tested/Suitable for anti-GAD65 antibody
Peptide ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-GAD65 antibody
Peptide ELISA: 1:40,000-1:80,000
WB: 1:200-500
IHC: 1:50-200

Testing Data of anti-GAD65 antibody
anti-GAD65 antibody Testing Data image
NCBI/Uniprot data below describe general gene information for GAD65. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
65,411 Da
NCBI Official Full Name
glutamate decarboxylase 2
NCBI Official Synonym Full Names
glutamate decarboxylase 2
NCBI Official Symbol
NCBI Official Synonym Symbols
GAD65
  [Similar Products]
NCBI Protein Information
glutamate decarboxylase 2
UniProt Protein Name
Glutamate decarboxylase 2
UniProt Synonym Protein Names
65 kDa glutamic acid decarboxylase; GAD-65; Glutamate decarboxylase 65 kDa isoform
UniProt Gene Name
UniProt Synonym Gene Names
GAD65; GAD-65  [Similar Products]
NCBI Summary for GAD65
This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Alternative splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Oct 2008]
UniProt Comments for GAD65
Catalyzes the production of GABA.
Product References and Citations for anti-GAD65 antibody
Oak, S., Gilliam, L.K., Landin-Olsson, M., et al.The lack of anti-idiotypic antibodies, not the presence of the corresponding autoantibodies to glutamate decarboxylase, defines type 1 diabetes. Proc. Natl. Acad. Sci. U.S.A. 105 (14), 5471-5476 (2008).

Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Organs/Tissues associated with anti-GAD65 antibody
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