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anti-GPM6A antibody :: Rabbit anti-Human GPM6A Polyclonal Antibody

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Catalog # MBS1499201
Unit / Price
  0.05 mg  /  $160 +1 FREE 8GB USB
  0.1 mg  /  $235 +1 FREE 8GB USB
Product Name

GPM6A, Polyclonal Antibody

Popular Item
Also Known As

GPM6A Antibody

Product Synonym Names
Neuronal membrane glycoprotein M6-a; M6a; GPM6A; M6A
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence Length
271
OMIM
601275
3D Structure
ModBase 3D Structure for P51674
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Purity/Purification
>95%, Protein G Purified
Storage Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Conjugate
Non-conjugated
Immunogen
Recombinant human Neuronal membrane glycoprotein M6-a protein
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-168523
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of anti-GPM6A antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-GPM6A antibody
Involved in neuronal differentiation, including differentiation and migration of neuronal stem cells. Plays a role in neuronal plasticity and is involved in neurite and filopodia outgrowth, filopodia motility and probably synapse formation. GPM6A-induced filopodia formation involves mitogen-activated protein kinase (MAPK) and Src signaling pathways. May be involved in neuronal NGF-dependent Ca(2+) influx. May be involved in regulation of endocytosis and intracellular trafficking of G-protein-coupled receptors (GPCRs); enhances internalization and recycling of mu-type opioid receptor.
Applications Tested/Suitable for anti-GPM6A antibody
ELISA (EIA), Western Blot (WB), Immunofluorescence (IF)

Western Blot (WB) of anti-GPM6A antibody
Western Blot
Positive WB detected in:Mouse liver tissue,Mouse spleen tissue,Mouse brain tissue,Mouse stomach tissue,Mouse skeletal muscle tissue
All lanes: GPM6A antibody at 4ug/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 32,31,30 kDa
Observed band size: 32 kDa

anti-GPM6A antibody Western Blot (WB) (WB) image
Immunofluorescence (IF) of anti-GPM6A antibody
Immunofluorescent analysis of MCF-7 cells using MBS1499201 at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
anti-GPM6A antibody Immunofluorescence (IF) image
NCBI/Uniprot data below describe general gene information for GPM6A. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
29,905 Da
NCBI Official Full Name
neuronal membrane glycoprotein M6-a isoform 4
NCBI Official Synonym Full Names
glycoprotein M6A
NCBI Official Symbol
GPM6A  [Similar Products]
NCBI Official Synonym Symbols
M6A; GPM6
  [Similar Products]
NCBI Protein Information
neuronal membrane glycoprotein M6-a
UniProt Protein Name
Neuronal membrane glycoprotein M6-a
UniProt Gene Name
GPM6A  [Similar Products]
UniProt Synonym Gene Names
M6A; M6a  [Similar Products]
UniProt Entry Name
GPM6A_HUMAN
UniProt Comments for GPM6A
GPM6A: Involved in neuronal differentiation, including differentiation and migration of neuronal stem cells. Plays a role in neuronal plasticity and is involved in neurite and filopodia outgrowth, filopodia motility and probably synapse formation. GPM6A-induced filopodia formation involves mitogen-activated protein kinase (MAPK) and Src signaling pathways. May be involved in neuronal NGF-dependent Ca(2+) influx. May be involved in regulation of endocytosis and intracellular trafficking of G- protein-coupled receptors (GPCRs); enhances internalization and recycling of mu-type opioid receptor. Belongs to the myelin proteolipid protein family.

Protein type: Channel, calcium; Cell surface; Membrane protein, multi-pass; Membrane protein, integral

Chromosomal Location of Human Ortholog: 4q34

Cellular Component: cell soma; dendritic spine; filopodium; integral to membrane; neuron projection; plasma membrane

Molecular Function: calcium channel activity; protein binding

Biological Process: neurite morphogenesis; neuron migration; positive regulation of filopodium formation; stem cell differentiation; synaptogenesis
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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