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anti-IID antibody :: Rabbit anti-Human Group IID secretory phospholipase A2 Polyclonal Antibody

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Catalog # MBS1490533
Unit / Price
  0.05 mg  /  $160 +1 FREE 8GB USB
  0.1 mg  /  $235 +1 FREE 8GB USB
Product Name

Group IID secretory phospholipase A2, Polyclonal Antibody

Popular Item
Also Known As

Rabbit anti-human Group IID secretory phospholipase A2 polyclonal Antibody

Product Synonym Names
GIID sPLA2; sPLA2-IID; PLA2IID; Phosphatidylcholine 2-acylhydrolase 2D; Secretory-type PLA; stroma-associated homolog
Product Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence Length
62
OMIM
605630
3D Structure
ModBase 3D Structure for Q9UNK4
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Purity/Purification
Caprylic Acid Ammonium Sulfate Precipitation Purified
Storage Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Conjugate
Non-conjugated
Immunogen
Recombinant human Group IID secretory phospholipase A2 protein
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-104296
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of anti-IID antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-IID antibody
PA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides. L-alpha-1-palmitoyl-2-linoleoyl phosphatidylethanolamine is more efficiently hydrolyzed than the other phospholipids examined.
Applications Tested/Suitable for anti-IID antibody
ELISA (EIA), Immunohistochemistry (IHC)

Immunohistochemistry (IHC) of anti-IID antibody
Immunohistochemistry of paraffin-embedded human kidney tissue using MBS1490533 at dilution 1:100
anti-IID antibody Immunohistochemistry (IHC) (IHC) image
Immunohistochemistry (IHC) of anti-IID antibody
Immunohistochemistry of paraffin-embedded human pancreatic tissue using MBS1490533 at dilution 1:100
anti-IID antibody Immunohistochemistry (IHC) (IHC) image
Immunohistochemistry (IHC) of anti-IID antibody
Immunohistochemistry of paraffin-embedded human melanoma cancer using MBS1490533 at dilution 1:100
anti-IID antibody Immunohistochemistry (IHC) (IHC) image
NCBI/Uniprot data below describe general gene information for IID. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
16,546 Da
NCBI Official Full Name
group IID secretory phospholipase A2 isoform 2
NCBI Official Synonym Full Names
phospholipase A2 group IID
NCBI Official Symbol
PLA2G2D  [Similar Products]
NCBI Official Synonym Symbols
SPLASH; sPLA2S; PLA2IID; sPLA2-IID
  [Similar Products]
NCBI Protein Information
group IID secretory phospholipase A2
UniProt Protein Name
Group IID secretory phospholipase A2
UniProt Synonym Protein Names
PLA2IID; Phosphatidylcholine 2-acylhydrolase 2D; Secretory-type PLA, stroma-associated homolog
UniProt Gene Name
PLA2G2D  [Similar Products]
UniProt Synonym Gene Names
SPLASH; GIID sPLA2; sPLA2-IID  [Similar Products]
UniProt Entry Name
PA2GD_HUMAN
NCBI Summary for IID
This gene encodes a secreted member of the phospholipase A2 family, and is found in a cluster of related family members on chromosome 1. Phospholipase A2 family members hydrolyze the sn-2 fatty acid ester bond of glycerophospholipids to produce lysophospholipids and free fatty acid. This gene may be involved in inflammation and immune response, and in weight loss associated with chronic obstructive pulmonary disease. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Nov 2012]
UniProt Comments for IID
PLA2G2D: PA2 catalyzes the calcium-dependent hydrolysis of the 2- acyl groups in 3-sn-phosphoglycerides. L-alpha-1-palmitoyl-2- linoleoyl phosphatidylethanolamine is more efficiently hydrolyzed than the other phospholipids examined. Belongs to the phospholipase A2 family.

Protein type: Secreted, signal peptide; Phospholipase; EC 3.1.1.4; Lipid Metabolism - ether lipid; Lipid Metabolism - alpha-linolenic acid; Lipid Metabolism - glycerophospholipid; Lipid Metabolism - linoleic acid; Lipid Metabolism - arachidonic acid; Secreted

Chromosomal Location of Human Ortholog: 1p36.12

Cellular Component: extracellular region

Molecular Function: calcium ion binding; heparan sulfate proteoglycan binding; heparin binding; phospholipase A2 activity

Biological Process: CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation; glycerophospholipid biosynthetic process; inflammatory response; lipid catabolic process; negative regulation of T cell proliferation; phosphatidic acid biosynthetic process; phospholipid metabolic process
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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