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anti-HBG1 antibody :: Rabbit anti-Human Hemoglobin subunit gamma-1 Polyclonal Antibody

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Catalog # MBS1489823
Unit / Price
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  0.05 mg  /  $160 +1 FREE 8GB USB
  0.1 mg  /  $235 +1 FREE 8GB USB
Immunohistochemistry (IHC)
Product Name

Hemoglobin subunit gamma-1 (HBG1), Polyclonal Antibody

Popular Item
Full Product Name

Rabbit anti-human Hemoglobin subunit gamma-1 polyclonal Antibody

Product Synonym Names
Gamma-1-globin; Hb F Agamma; Hemoglobin gamma-1 chain; Hemoglobin gamma-A chain; PRO2979
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
OMIM
142200
3D Structure
ModBase 3D Structure for P69891
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Purity/Purification
Caprylic Acid Ammonium Sulfate Precipitation Purified
Storage Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Conjugate
Non-conjugated
Immunogen
Recombinant human Hemoglobin subunit gamma-1 protein
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of anti-HBG1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-HBG1 antibody
Gamma chains make up the fetal hemoglobin F, in combination with alpha chains.
Applications Tested/Suitable for anti-HBG1 antibody
ELISA (EIA), Immunohistochemistry (IHC)

Immunohistochemistry (IHC) of anti-HBG1 antibody
Immunohistochemistry of paraffin-embedded human liver tissue using MBS1489823 at dilution 1:100
anti-HBG1 antibody Immunohistochemistry (IHC) (IHC) image
NCBI/Uniprot data below describe general gene information for HBG1. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
16,140 Da
NCBI Official Full Name
hemoglobin subunit gamma-1
NCBI Official Synonym Full Names
hemoglobin subunit gamma 1
NCBI Official Symbol
NCBI Official Synonym Symbols
HBGA; HBGR; HBG-T2; HSGGL1; PRO2979
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NCBI Protein Information
hemoglobin subunit gamma-1
UniProt Protein Name
Hemoglobin subunit gamma-1
UniProt Synonym Protein Names
Gamma-1-globin; Hb F Agamma; Hemoglobin gamma-1 chain; Hemoglobin gamma-A chain
Protein Family
UniProt Gene Name
UniProt Entry Name
HBG1_HUMAN
NCBI Summary for HBG1
The gamma globin genes (HBG1 and HBG2) are normally expressed in the fetal liver, spleen and bone marrow. Two gamma chains together with two alpha chains constitute fetal hemoglobin (HbF) which is normally replaced by adult hemoglobin (HbA) at birth. In some beta-thalassemias and related conditions, gamma chain production continues into adulthood. The two types of gamma chains differ at residue 136 where glycine is found in the G-gamma product (HBG2) and alanine is found in the A-gamma product (HBG1). The former is predominant at birth. The order of the genes in the beta-globin cluster is: 5'-epsilon -- gamma-G -- gamma-A -- delta -- beta--3'. [provided by RefSeq, Jul 2008]
UniProt Comments for HBG1
HBG1: Gamma chains make up the fetal hemoglobin F, in combination with alpha chains. Belongs to the globin family.

Protein type: Carrier

Chromosomal Location of Human Ortholog: 11p15.5

Cellular Component: cytosol; hemoglobin complex

Molecular Function: heme binding; iron ion binding; oxygen binding; oxygen transporter activity

Biological Process: blood coagulation; oxygen transport

Disease: Fetal Hemoglobin Quantitative Trait Locus 1
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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