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anti-HPV11 E6 antibody :: Goat HPV11 E6 Polyclonal Antibody

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Catalog # MBS448009 (SPECIAL PROMOTIONAL PRICING for a limited time)
Unit / Price
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  0.6 mg  /  $285 +1 FREE 8GB USB
Product Name

HPV11 E6, Polyclonal Antibody

Popular Item
Full Product Name

HPV11 E6 Polyclonal Antibody

Product Synonym Names
Anti-HPV11 E6
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Clonality
Polyclonal
Isotype
IgG
Host
Goat
Species Reactivity
Human papilloma viruses type 11
Specificity
Detects HPV11 E6 recombinant fusion proteins MBP-E6 and GFP-E6 expressed in transfected mammalian cells.
Form/Format
Polyclonal antibody supplied as (3 mg/ml) aliquot in PBS, 20% glycerol and 0.05% sodium azide. This antibody is epitope-affinity purified from goat antiserum.
Immunogen
Purified recombinant peptide derived from within residues 65 aa to N-terminal of HPV11 E6 produced in E. coli.
Antigen
Purified recombinant peptide derived from within residues 65 aa to N-terminal of HPV11 E6 produced in E. coli.
Handling
The antibody solution should be gently mixed before use.
Preparation and Storage
For continuous use, store at 2-8 deg;C for one-two days. For extended storage, store in -20 deg;C freezer. Working dilution samples should be discarded if not used within 12 hours.
Other Notes
Small volumes of anti-HPV11 E6 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-HPV11 E6 antibody
Goat polyclonal antibody to HPV11 E6. E6 is one primary oncoprotein of high risk HPV types expressed early in the HPV life cycle. After the host cell is infected viral early promoter is activated and a polycistronic primary RNA containing all six early ORFs is transcribed. This polycistronic RNA then undergoes active RNA splicing to generate multiple isoforms of mRNAs. One of the spliced isoform RNAs, E6, serves as an E7 mRNA to translate E7 protein. HPV genome integrate into host genome by disruption of E2 ORF, preventing E2 repression on E6 and E7. Thus, viral genome integration into host DNA genome increases E6 expression. The E6 protein inactivates the tumour suppressor protein, p53 and promote cellular proliferation and the chance of malignancy.
Applications Tested/Suitable for anti-HPV11 E6 antibody
Western Blot (WB)
Application Notes for anti-HPV11 E6 antibody
Western Blot: 1:500-1:2,000

Reactivity Chart of anti-HPV11 E6 antibody
anti-HPV11 E6 antibody Reactivity Chart image
Testing Data of anti-HPV11 E6 antibody
anti-HPV11 E6 antibody Testing Data image
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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