anti-ICE1 antibody :: Rabbit anti-Human ICE1 Polyclonal Antibody
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Purity/Purification
>95%, Protein G purified
Immunogen
Recombinant human Little elongation complex subunit 1 protein
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-243172 / sc-243173
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Other Notes
Small volumes of anti-ICE1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
|
Related Product Information for
anti-ICE1 antibody
Component of the little elongation complex (LEC), a complex required to regulate small nuclear RNA (snRNA) gene transcription by RNA polymerase II and III (PubMed:22195968, PubMed:23932780). Specifically acts as a scaffold protein that promotes the LEC complex formation and recruitment and RNA polymerase II occupancy at snRNA genes in subnuclear bodies (PubMed:23932780).
|
Applications Tested/Suitable for
anti-ICE1 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Immunohistochemistry (IHC) of
anti-ICE1 antibody
Immunohistochemistry of paraffin-embedded human thyroid tissue using MBS7045971 at dilution of 1:100
Immunohistochemistry (IHC) of
anti-ICE1 antibody
Immunohistochemistry of paraffin-embedded human adrenal gland tissue using MBS7045971 at dilution of 1:100
Western Blot (WB) of
anti-ICE1 antibody
Western Blot
Positive WB detected in:mouse brain tissue
All lanes: ICE1 antibody at 2.7ug/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 68 kDa
Observed band size: 68 kDa
NCBI/Uniprot data below describe general gene information for
ICE1. It may not necessarily be applicable to this product.
NCBI Accession #
NP_056140.1
[Other Products]
NCBI GenBank Nucleotide #
|
[Other Products]
UniProt Primary Accession #
|
[Other Products]
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
247,891 Da
NCBI Official Full Name
little elongation complex subunit 1
NCBI Official Synonym Full Names
interactor of little elongation complex ELL subunit 1
NCBI Official Synonym Symbols
NCBI Protein Information
little elongation complex subunit 1
UniProt Protein Name
Little elongation complex subunit 1
UniProt Synonym Protein Names
Interactor of little elongator complex ELL subunit 1
UniProt Synonym Gene Names
UniProt Entry Name
ICE1_HUMAN
UniProt Comments for ICE1
ICE1: protein of unknown function.
Protein type: Unknown function
Chromosomal Location of Human Ortholog: 5p15.32
Cellular Component: Cajal body; nucleoplasm; transcription elongation factor complex
Molecular Function: protein binding; protein homodimerization activity
Biological Process: positive regulation of protein complex assembly; positive regulation of transcription from RNA polymerase III promoter; snRNA transcription from RNA polymerase II promoter; snRNA transcription from RNA polymerase III promoter
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice. It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Pathways associated with anti-ICE1 antibody
Organs/Tissues associated with anti-ICE1 antibody
|