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anti-IFNAR1 antibody :: Rabbit anti-Human IFNAR1 Polyclonal Antibody

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Catalog # MBS2527835
Unit / Price
  0.06 mL  /  $150 +1 FREE 8GB USB
  0.12 mL  /  $225 +1 FREE 8GB USB
  0.2 mL  /  $360 +1 FREE 8GB USB
Product Name

IFNAR1, Polyclonal Antibody

Popular Item
Also Known As

IFNAR1 Antibody

Product Synonym Names
AVP; IFRC; IFNAR; IFNBR; IFN-alpha-REC
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence Length
557
OMIM
107450
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Purity/Purification
Affinity purification
Concentration
1mg/mL (lot specific)
Immunogen
Recombinant protein of human IFNAR1
Observed Molecular Weight
63kDa
Buffer
PBS with 0.1% sodium azide, 50% glycerol, pH7.3
Preparation and Storage
Store at -20 degree C. Avoid freeze / thaw cycles.
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of anti-IFNAR1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-IFNAR1 antibody
The protein encoded by this gene is a type I membrane protein that forms one of the two chains of a receptor for interferons alpha and beta. Binding and activation of the receptor stimulates Janus protein kinases, which in turn phosphorylate several proteins, including STAT1 and STAT2. The encoded protein also functions as an antiviral factor.
Applications Tested/Suitable for anti-IFNAR1 antibody
Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-IFNAR1 antibody
WB 1:500 - 1:2000
IHC 1:50 - 1:200

Western Blot (WB) of anti-IFNAR1 antibody
Western blot analysis of extracts of various cell lines, using IFNAR1 antibody.
anti-IFNAR1 antibody Western Blot (WB) (WB) image
Immunohistochemistry (IHC) of anti-IFNAR1 antibody
Immunohistochemistry of paraffin-embedded human liver cancer using IFNAR1 antibody at dilution of 1:200 (x400 lens)
anti-IFNAR1 antibody Immunohistochemistry (IHC) (IHC) image
NCBI/Uniprot data below describe general gene information for IFNAR1. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
56,046 Da
NCBI Official Full Name
interferon alpha/beta receptor 1
NCBI Official Synonym Full Names
interferon (alpha, beta and omega) receptor 1
NCBI Official Symbol
IFNAR1  [Similar Products]
NCBI Official Synonym Symbols
AVP; IFRC; IFNAR; IFNBR; IFN-alpha-REC
  [Similar Products]
NCBI Protein Information
interferon alpha/beta receptor 1; CRF2-1; IFN-R-1; IFN-alpha/beta receptor 1; alpha-type antiviral protein; beta-type antiviral protein; cytokine receptor class-II member 1; cytokine receptor family 2 member 1; interferon-alpha/beta receptor alpha chain; interferon-beta receptor 1; type I interferon receptor 1
UniProt Protein Name
Interferon alpha/beta receptor 1
UniProt Synonym Protein Names
Cytokine receptor class-II member 1; Cytokine receptor family 2 member 1; CRF2-1; Type I interferon receptor 1
UniProt Gene Name
IFNAR1  [Similar Products]
UniProt Synonym Gene Names
IFNAR; IFN-R-1; IFN-alpha/beta receptor 1; CRF2-1  [Similar Products]
UniProt Entry Name
INAR1_HUMAN
NCBI Summary for IFNAR1
The protein encoded by this gene is a type I membrane protein that forms one of the two chains of a receptor for interferons alpha and beta. Binding and activation of the receptor stimulates Janus protein kinases, which in turn phosphorylate several proteins, including STAT1 and STAT2. The encoded protein also functions as an antiviral factor. [provided by RefSeq, Jul 2008]
UniProt Comments for IFNAR1
IFNAR1: receptor for interferons alpha and beta. Belongs to the type II cytokine family of receptors. Binding to type I IFNs triggers tyrosine phosphorylation of a number of proteins including JAKs, TYK2, STAT proteins and IFNR alpha- and beta-subunits themselves. Tyk2 tyrosine kinase is essential for stable cell surface expression of IFNAR1. Present in all tissues and even on the surface of most IFN-resistant cells.

Protein type: Membrane protein, integral; Receptor, cytokine

Chromosomal Location of Human Ortholog: 21q22.11

Cellular Component: integral to plasma membrane; plasma membrane; integral to membrane

Molecular Function: protein binding; interferon receptor activity; interferon-alpha/beta receptor activity

Biological Process: positive regulation of interferon-gamma production; cell surface receptor linked signal transduction; T cell activation; response to virus; cytokine and chemokine mediated signaling pathway; positive regulation of interleukin-1 beta secretion; interferon type I biosynthetic process; JAK-STAT cascade; defense response to virus
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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