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anti-INSL3 antibody :: Rabbit anti-Human INSL3 Polyclonal Antibody

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Catalog # MBS9601400
Unit / Price
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  0.1 mL  /  $255 +1 FREE 8GB USB
  0.2 mL  /  $295 +1 FREE 8GB USB
Western Blot (WB)
Product Name

INSL3, Polyclonal Antibody

Popular Item
Full Product Name

INSL3 Antibody

Product Synonym Names
INSL 3; INSL3; INSL3_HUMAN; Insulin like 3; insulin like peptide, Leydig cell-specific; insulin-like 3 (Leydig cell); Insulin-like 3 A chain; Ley IL; Ley-I-L; leydig insulin-like hormone; Leydig insulin like peptide; Leydig insulin-like peptide; prepro-INSL3; Relaxin like factor; Relaxin-like factor; relaxin-like factor b; RLF; RLNL
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for P51460
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Specificity
INSL3 antibody detects endogenous levels of total INSL3
Purity/Purification
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
Form/Format
Liquid
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1mg/ml (lot specific)
Immunogen
A synthesized peptide derived from human INSL3
Subcellular Location
Secreted.
Tissue Specificity
Expressed in prenatal and postnatal Leydig cells. Found as well in the corpus luteum, trophoblast, fetal membranes and breast.
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C. Stable for 12 months from date of receipt.
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Supply Chain Verification
Manufactured in a lab with traceable raw materials manufactured on site. Coordinated product portfolio of antibodies, pairs, conjugates, recombinant proteins, and immunoassay materials available, please inquire.
Other Notes
Small volumes of anti-INSL3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-INSL3 antibody
Description: Seems to play a role in testicular function. May be a trophic hormone with a role in testicular descent in fetal life. Is a ligand for LGR8 receptor.
Subunit Structure: Heterodimer of a B chain and an A chain linked by two disulfide bonds.
Similarity: Belongs to the insulin family.
Applications Tested/Suitable for anti-INSL3 antibody
Western Blot (WB), ELISA (EIA)
Application Notes for anti-INSL3 antibody
WB: 1:500-1:2000

Western Blot (WB) of anti-INSL3 antibody
Western blot analysis of INSL3 expression in MCF7 cells, The lane on the left is treated with the antigen-specific peptide.
anti-INSL3 antibody Western Blot (WB) (WB) image
NCBI/Uniprot data below describe general gene information for INSL3. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
Observed: 14 kDa
Predicted: 15 kDa
NCBI Official Full Name
insulin-like 3 isoform 1
NCBI Official Synonym Full Names
insulin like 3
NCBI Official Symbol
INSL3  [Similar Products]
NCBI Official Synonym Symbols
RLF; RLNL; ley-I-L
  [Similar Products]
NCBI Protein Information
insulin-like 3
UniProt Protein Name
Insulin-like 3
UniProt Synonym Protein Names
Leydig insulin-like peptide; Ley-I-L
Protein Family
UniProt Gene Name
INSL3  [Similar Products]
UniProt Synonym Gene Names
RLF; RLNL; Ley-I-L  [Similar Products]
NCBI Summary for INSL3
This gene encodes a member of the insulin-like hormone superfamily. The encoded protein is mainly produced in gonadal tissues. Studies of the mouse counterpart suggest that this gene may be involved in the development of urogenital tract and female fertility. This protein may also act as a hormone to regulate growth and differentiation of gubernaculum, and thus mediating intra-abdominal testicular descent. Mutations in this gene may lead to cryptorchidism. Alternate splicing results in multiple transcript variants. [provided by RefSeq, May 2012]
UniProt Comments for INSL3
Seems to play a role in testicular function. May be a trophic hormone with a role in testicular descent in fetal life. Is a ligand for LGR8 receptor.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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