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anti-ITGB6 antibody :: Rabbit anti-Human integrin, beta 6 Polyclonal Antibody

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Catalog # MBS712187
Unit / Price
  0.05 mL  /  $230 +1 FREE 8GB USB
  0.15 mL  /  $500 +1 FREE 8GB USB
anti-ITGB6 antibody
Product Name

integrin, beta 6 (ITGB6), Polyclonal Antibody

Also Known As

Rabbit anti-human integrin, beta 6 polyclonal Antibody

Product Synonym Names
integrin; beta 6;
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence Length
788
OMIM
147558
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Purity/Purification
Antigen Affinity Purified
Immunogen
Human ITGB6-Specific
Storage Buffer
PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20 degree C, Avoid freeze / thaw cycles.
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-6633 / sc-6632 / sc-15329
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of anti-ITGB6 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-ITGB6 antibody
ELISA (EIA), Western Blot (WB)
NCBI/Uniprot data below describe general gene information for ITGB6. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
74,958 Da[Similar Products]
NCBI Official Full Name
Integrin, beta 6
NCBI Official Synonym Full Names
integrin, beta 6
NCBI Official Symbol
ITGB6  [Similar Products]
NCBI Protein Information
integrin beta-6
UniProt Protein Name
Integrin beta-6
Protein Family
UniProt Gene Name
ITGB6  [Similar Products]
UniProt Entry Name
ITB6_HUMAN
NCBI Summary for ITGB6
This gene encodes a protein that is a member of the integrin superfamily. Members of this family are adhesion receptors that function in signaling from the extracellular matrix to the cell. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. The encoded protein forms a dimer with an alpha v chain and this heterodimer can bind to ligands like fibronectin and transforming growth factor beta 1. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]
UniProt Comments for ITGB6
ITGB6: Integrin alpha-V/beta-6 is a receptor for fibronectin and cytotactin. It recognizes the sequence R-G-D in its ligands. Internalisation of integrin alpha-V/beta-6 via clathrin-mediated endocytosis promotes carcinoma cell invasion. Belongs to the integrin beta chain family.

Protein type: Motility/polarity/chemotaxis; Membrane protein, integral; Cell adhesion

Chromosomal Location of Human Ortholog: 2q24.2

Cellular Component: plasma membrane; integrin complex; receptor complex; external side of plasma membrane

Molecular Function: integrin binding; viral receptor activity

Biological Process: integrin-mediated signaling pathway; extracellular matrix organization and biogenesis; entry of virus into host cell; multicellular organismal development; cell-matrix adhesion; inflammatory response; cell adhesion

Disease: Amelogenesis Imperfecta, Type Ih
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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