NP_002166.2
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
interferon alpha-21
NCBI Official Synonym Full Names
interferon, alpha 21
NCBI Protein Information
interferon alpha-21
UniProt Protein Name
Interferon alpha-21
UniProt Synonym Protein Names
Interferon alpha-F; LeIF F
UniProt Synonym Gene Names
UniProt Entry Name
IFN21_HUMAN
NCBI Summary for IFNA21
This gene is a member of the alpha interferon gene cluster on the short arm of chromosome 9. Interferons are cytokines produced in response to viral infection that mediate the immune response and interfere with viral replication. The encoded protein is a type I interferon and may play a specific role in the antiviral response to rubella virus. [provided by RefSeq, Sep 2011]
UniProt Comments for IFNA21
IFNA21: Produced by macrophages, IFN-alpha have antiviral activities. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase. Belongs to the alpha/beta interferon family.
Protein type: Secreted; Secreted, signal peptide; Cytokine
Chromosomal Location of Human Ortholog: 9p22
Cellular Component: extracellular region; extracellular space
Molecular Function: cytokine activity; hematopoietin/interferon-class (D200-domain) cytokine receptor binding; interferon-alpha/beta receptor binding
Biological Process: adaptive immune response; B cell differentiation; B cell proliferation; blood coagulation; cytokine and chemokine mediated signaling pathway; defense response to virus; humoral immune response; innate immune response; natural killer cell activation during immune response; positive regulation of peptidyl-serine phosphorylation of STAT protein; response to exogenous dsRNA; T cell activation during immune response
Research Articles on IFNA21
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Products associated with anti-IFNA21 antibody
Pathways associated with anti-IFNA21 antibody
Diseases associated with anti-IFNA21 antibody
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