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anti-IFNAR2 antibody :: Rabbit anti-Human interferon (alpha, beta and omega) receptor 2 Polyclonal Antibody

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Catalog # MBS716960
Unit / Price
  0.05 mL  /  $230 +1 FREE 8GB USB
  0.15 mL  /  $500 +1 FREE 8GB USB
anti-IFNAR2 antibody
Product Name

interferon (alpha, beta and omega) receptor 2 (IFNAR2), Polyclonal Antibody

Full Product Name

Rabbit anti-human interferon (alpha, beta and omega) receptor 2 polyclonal Antibody

Product Synonym Names
interferon (alpha; beta and omega) receptor 2; IFNAR2; IFN-R; IFN-alpha-REC; IFNABR; IFNARB
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
OMIM
gene 610424
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Purity/Purification
Antigen Affinity Purified
Immunogen
Human IFNAR2
Storage Buffer
PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20 degree C, Avoid freeze / thaw cycles.
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-83256 / sc-83257 / sc-83258 / sc-704 / sc-30014
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of anti-IFNAR2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-IFNAR2 antibody
ELISA (EIA), Western Blot (WB)
NCBI/Uniprot data below describe general gene information for IFNAR2. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
27,384 Da[Similar Products]
NCBI Official Full Name
interferon (alpha, beta and omega) receptor 2, isoform CRA_b
NCBI Official Synonym Full Names
interferon (alpha, beta and omega) receptor 2
NCBI Official Symbol
IFNAR2  [Similar Products]
NCBI Official Synonym Symbols
IFN-R; IFNABR; IFNARB; IFN-alpha-REC
  [Similar Products]
NCBI Protein Information
interferon alpha/beta receptor 2; IFN-R-2; IFN-alpha/beta receptor 2; type I interferon receptor 2; interferon alpha binding protein; human interferon alpha/beta receptor; interferon-alpha/beta receptor beta chain
UniProt Protein Name
Interferon alpha/beta receptor 2
UniProt Synonym Protein Names
Interferon alpha binding protein; Type I interferon receptor 2
UniProt Gene Name
IFNAR2  [Similar Products]
UniProt Synonym Gene Names
IFNABR; IFNARB; IFN-R-2; IFN-alpha binding protein; IFN-alpha/beta receptor 2  [Similar Products]
UniProt Entry Name
INAR2_HUMAN
NCBI Summary for IFNAR2
The protein encoded by this gene is a type I membrane protein that forms one of the two chains of a receptor for interferons alpha and beta. Binding and activation of the receptor stimulates Janus protein kinases, which in turn phosphorylate several proteins, including STAT1 and STAT2. Multiple transcript variants encoding at least two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
UniProt Comments for IFNAR2
IFNAR2: Associates with IFNAR1 to form the type I interferon receptor. Receptor for interferons alpha and beta. Involved in IFN-mediated STAT1, STAT2 and STAT3 activation. Isoform 1 and isoform 2 are directly involved in signal transduction due to their association with the TYR kinase, JAK1. Isoform 3 is a potent inhibitor of type I IFN receptor activity. Belongs to the type II cytokine receptor family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Receptor, cytokine

Chromosomal Location of Human Ortholog: 21q22.11

Cellular Component: extracellular space; integral to plasma membrane; extracellular region; plasma membrane

Molecular Function: protein binding; interferon-alpha/beta receptor activity; interferon-alpha/beta binding; protein kinase binding

Biological Process: regulation of transcription from RNA polymerase II promoter; cell proliferation; cell surface receptor linked signal transduction; cytokine and chemokine mediated signaling pathway; response to virus; JAK-STAT cascade

Disease: Hepatitis B Virus, Susceptibility To
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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