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anti-IL15 antibody :: Rabbit anti-Human Interleukin 15 (IL15) Polyclonal Antibody

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Catalog # MBS2004677 (SPECIAL PROMOTION: Get FREE $5 Starbucks gift card (Maximum 5 gift cards/product). Gift card(s) will be included with shipment)
Unit / Price
  0.01 mg  /  $90 +1 FREE 8GB USB
  0.02 mg  /  $105 +1 FREE 8GB USB
  0.05 mg  /  $135 +1 FREE 8GB USB
  0.1 mg  /  $165 +1 FREE 8GB USB
  0.2 mg  /  $230 +1 FREE 8GB USB
  1 mg  /  $515 +1 FREE 8GB USB
Product Name

Interleukin 15 (IL15), Polyclonal Antibody

Popular Item
Also Known As

Polyclonal Antibody to Interleukin 15 (IL15)

Matching Pairs
Unconjugated Antibody: Interleukin 15 (IL15) (MBS2004677)
Biotin Conjugated Antibody: Interleukin 15 (IL15) (MBS2004115)
Matching Pairs
Matching Pairs
Unconjugated Antibody: Interleukin 15 (IL15) (MBS2004677)
APC-CY7 Conjugated Antibody: Interleukin 15 (IL15) (MBS2036434)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
OMIM
U14407 mRNA
3D Structure
ModBase 3D Structure for P40933
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Specificity
The antibody is a Rabbit polyclonal antibody raised against IL15. It has been selected for its ability to recognize IL15 in immunohistochemical staining and western blotting.
Purity/Purification
Antigen-specific Affinity Chromatography
Form/Format
Supplied as solution form in 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol
Concentration
200µg/mL (lot specific)
Source
Polyclonal antibody preparation
Traits
Liquid
Immunogen
Recombinant IL15 (Trp50~Ser162) expressed in E.coli.
Conjugated Antibody
The APC conjugated antibody version of this item is also available as catalog #MBS2036436
Preparation and Storage
Storage: Avoid repeated freeze/thaw cycles.
Store at 4°C for frequent use.
Aliquot and store at -20°C for 12 months.
Stability Test: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Other Notes
Small volumes of anti-IL15 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-IL15 antibody
WB; IHC; ICC; IP
Application Notes for anti-IL15 antibody
Western blotting: 0.5-2µg/mL
Immunohistochemistry: 5-20µg/mL
Immunocytochemistry: 5-20µg/mL

Optimal working dilutions must be determined by end user

Western Blot (WB) of anti-IL15 antibody
Western Blot: Sample: Recombinant IL15, Human.
anti-IL15 antibody Western Blot (WB) (WB) image
Immunohistochemistry (IHC) of anti-IL15 antibody
DAB staining on IHC-P; Samples: Human Pancreas Cancer Tissue
anti-IL15 antibody Immunohistochemistry (IHC) (IHC) image
Immunohistochemistry (IHC) of anti-IL15 antibody
DAB staining on IHC-P; Samples: Human Liver Cancer Tissue.
anti-IL15 antibody Immunohistochemistry (IHC) (IHC) image
Immunohistochemistry (IHC) of anti-IL15 antibody
DAB staining on IHC-P; Samples: Human Stomach Tissue.
anti-IL15 antibody Immunohistochemistry (IHC) (IHC) image
Immunohistochemistry (IHC) of anti-IL15 antibody
DAB staining on IHC-P; Samples: Human Kidney Tissue.
anti-IL15 antibody Immunohistochemistry (IHC) (IHC) image
NCBI/Uniprot data below describe general gene information for IL15. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
14,912 Da
NCBI Official Full Name
interleukin-15 isoform 1 preproprotein
NCBI Official Synonym Full Names
interleukin 15
NCBI Official Symbol
NCBI Official Synonym Symbols
IL-15
  [Similar Products]
NCBI Protein Information
interleukin-15
UniProt Protein Name
Interleukin-15
Protein Family
UniProt Gene Name
UniProt Synonym Gene Names
IL-15  [Similar Products]
NCBI Summary for IL15
The protein encoded by this gene is a cytokine that regulates T and natural killer cell activation and proliferation. This cytokine and interleukine 2 share many biological activities. They are found to bind common hematopoietin receptor subunits, and may compete for the same receptor, and thus negatively regulate each other's activity. The number of CD8+ memory cells is shown to be controlled by a balance between this cytokine and IL2. This cytokine induces the activation of JAK kinases, as well as the phosphorylation and activation of transcription activators STAT3, STAT5, and STAT6. Studies of the mouse counterpart suggested that this cytokine may increase the expression of apoptosis inhibitor BCL2L1/BCL-x(L), possibly through the transcription activation activity of STAT6, and thus prevent apoptosis. Alternatively spliced transcript variants of this gene have been reported. [provided by RefSeq, Feb 2011]
UniProt Comments for IL15
IL15: Cytokine that stimulates the proliferation of T- lymphocytes. Stimulation by IL-15 requires interaction of IL-15 with components of IL-2R, including IL-2R beta and probably IL-2R gamma but not IL-2R alpha. Belongs to the IL-15/IL-21 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Cell cycle regulation; Cytokine; Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 4q31.21

Cellular Component: cell surface; cytoplasm; cytosol; endosome; extracellular region; extracellular space; Golgi apparatus; integral component of plasma membrane; membrane; nuclear speck; nucleoplasm

Molecular Function: cytokine activity; cytokine receptor binding; protein binding

Biological Process: aging; cell maturation; cell-cell signaling; extrathymic T cell selection; hyaluronan metabolic process; immune response; inflammatory response; lymph node development; natural killer cell differentiation; negative regulation of smooth muscle cell proliferation; NK T cell proliferation; positive regulation of cell proliferation; positive regulation of immune response; positive regulation of inflammatory response; positive regulation of interleukin-17 production; positive regulation of natural killer cell differentiation; positive regulation of natural killer cell proliferation; positive regulation of T cell proliferation; positive regulation of tissue remodeling; positive regulation of tyrosine phosphorylation of STAT protein; regulation of defense response to virus by host; regulation of T cell differentiation; signal transduction; skeletal muscle atrophy; tyrosine phosphorylation of STAT protein
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Organs/Tissues associated with anti-IL15 antibody
 Organ/Tissue Name  Pubmed Publications
 Mixed Antibodies  >40 publications with IL15 and Mixed
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