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anti-jak2b antibody :: Rabbit anti-Human JAK2 Polyclonal Antibody

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Catalog # MBS621761
Unit / Price
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  0.1 mg  /  $455 +1 FREE 8GB USB
anti-jak2b antibody
Product Name

JAK2 (jak2b), Polyclonal Antibody

Full Product Name

JAK2 (Janus Kinase 2)

Product Synonym Names
Anti -JAK2 (Janus Kinase 2)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Chromosome Location
Chromosome: 5; NC_007116.5 (69030569..69106033). Location: chromosome: 5
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Specificity
Recognizes endogenous levels of human total Jak2 protein.
Purity/Purification
Affinity Purified
Purified by immunoaffinity chromatography.
Form/Format
Supplied as a liquid in PBS without Mg2+ and Ca2+), pH 7.4, 0.02% sodium azide, 50% glycerol.
Immunogen
Synthesized non-phosphopeptide derived from human Jak2 around the phosphorylation site of tyrosine 570 (G-D-YP-G-Q).
Preparation and Storage
May be stored at 4 degree C for short-term only. For long-term storage, aliquot and store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Other Notes
Small volumes of anti-jak2b antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-jak2b antibody
The Janus (JAK) family of cytoplasmic tyrosine kinases has been implicated in signal transduction induced by cytokines and growth factors, physically associated with ligand-bound receptors. This association that results in tyrosine phosphorylation and activation. JAK1 is approximately 130kD and contains a C-terminal tyrosine kinase domain, an adjacent kinase or kinase-related domain, and five other domains that are highly conserved among JAK family members. Family members such as JAK1, JAK2, and TYK2 are ubiquitous, whereas JAK3 is predominantly expressed in T lymphocytes. Studies with mutant cells that do not express JAK1, JAK2, or TYK2 show that their activation is essential for cellular signaling. JAK family kinases may either phosphorylate each other or be phosphorylated by a yet undescribed tyrosine kinase. Different cytokines can activate via phosphorylation distinct JAK family members. In some cells, the membrane-associated gp130 protein has been implicated in the induction of JAK family phosphorylation, although gp130 itself has no known activity.
Applications Tested/Suitable for anti-jak2b antibody
Immunohistochemistry (IHC)
Application Notes for anti-jak2b antibody
Suitable for use in Immunohistochemistry.
Dilution: Immunohistochemistry: 1:50-1:100
NCBI/Uniprot data below describe general gene information for jak2b. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI Official Full Name
jak2
NCBI Official Synonym Full Names
Janus kinase 2b
NCBI Official Symbol
jak2b  [Similar Products]
NCBI Official Synonym Symbols
jak2; JAK2bCA
  [Similar Products]
NCBI Protein Information
tyrosine-protein kinase JAK2; PTK JAK2b; Jak2b kinase; protein tyrosine kinase JAK2b
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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