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anti-KLK2 antibody :: Rabbit anti-Human Kallikrein 2 Polyclonal Antibody

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Catalog # MBS175260
Unit / Price
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  0.1 mg  /  $315 +1 FREE 8GB USB
Product Name

Kallikrein 2 (KLK2), Polyclonal Antibody

Full Product Name

Anti-Kallikrein 2 antibody

Product Synonym Names
Kallikrein-2; kallikrein-related peptidase 2; Glandular kallikrein 2 antibody; Glandular kallikrein-1 antibody; hGK 1 antibody; hGK-1 antibody; hK2 antibody; Kallikrein 2 prostatic antibody; Kallikrein related peptidase 2 antibody; kallikrein, glandular antibody; Kallikrein, prostatic antibody; Kallikrein-2 antibody; KLK 2 antibody; Klk-2 antibody; Klk2 antibody; KLK2_HUMAN antibody; KLK2A 2 antibody; KLK2A2 antibody; MGC12201 antibody; Tissue kallikrein 2 antibody; Tissue kallikrein-2 antibody; Ton antibody
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
OMIM
147960
3D Structure
ModBase 3D Structure for P20151
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Purity/Purification
Immunogen affinity purified.
Form/Format
Lyophilized
Immunogen
A synthetic peptide corresponding to a sequence at the C-terminus of human Kallikrein 2 (243-261aa YTKVVHYRKWIKDTIAANP).
Contents
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
Reconstitution
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Preparation and Storage
At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of anti-KLK2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-KLK2 antibody
Description: Rabbit IgG polyclonal antibody for Kallikrein-2(KLK2) detection. Tested with WB, IHC-P in Human.
Background: KLK2(KALLIKREIN 2), also called GLANDULAR or PROSTATIC, is a protein that in humans is encoded by the KLK2 gene, and is particularly associated with prostatic tissue. The KLK2 is a member of glandular kallikrein gene family that comprises 25 to 30 highly homologous genes that encode specific proteases involved in the processing of biologically active peptides. The KLK2 gene is mapped to 19q13.33. And the KLK2 gene contains 5 exons. An alternative KLK2 transcript, which they call KLK2-linked molecule(KLM), that arises from the use of an alternate donor site within intron 1. KLM shares only the N-terminal 15-amino acid signal peptide with the original KLK2 protein; the mature proteins display no similarity.
Applications Tested/Suitable for anti-KLK2 antibody
Western Blot (WB), Immunohistochemistry (IHC) Paraffin

Immunohistochemistry (IHC) of anti-KLK2 antibody
Anti-Kallikrein 2 antibody, MBS175260, IHC(P)
IHC(P): Human Prostatic Cancer Tissue
anti-KLK2 antibody Immunohistochemistry (IHC) (IHC) image
Western Blot (WB) of anti-KLK2 antibody
Anti-Kallikrein 2 antibody, MBS175260, Western blotting
All lanes: Anti Kallikrein 2 (MBS175260) at 0.5ug/ml
Lane 1: PANC Whole Cell Lysate at 40ug
Lane 2: HELA Whole Cell Lysate at 40ug
Lane 3: 293T Whole Cell Lysate at 40ug
Predicted bind size: 29KD
Observed bind size: 29KD
anti-KLK2 antibody Western Blot (WB) (WB) image
NCBI/Uniprot data below describe general gene information for KLK2. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
17,301 Da
NCBI Official Full Name
Kallikrein-2
NCBI Official Synonym Full Names
kallikrein-related peptidase 2
NCBI Official Symbol
NCBI Official Synonym Symbols
hK2; hGK-1; KLK2A2
  [Similar Products]
NCBI Protein Information
kallikrein-2; tissue kallikrein-2; glandular kallikrein 2; glandular kallikrein-1; kallikrein 2, prostatic
UniProt Protein Name
Kallikrein-2
UniProt Synonym Protein Names
Glandular kallikrein-1; hGK-1; Tissue kallikrein-2
Protein Family
UniProt Gene Name
UniProt Synonym Gene Names
hGK-1  [Similar Products]
UniProt Entry Name
KLK2_HUMAN
NCBI Summary for KLK2
This gene encodes a member of the grandular kallikrein protein family. Kallikreins are a subgroup of serine proteases that are clustered on chromosome 19. Members of this family are involved in a diverse array of biological functions. The protein encoded by this gene is a highly active trypsin-like serine protease that selectively cleaves at arginine residues. This protein is primarily expressed in prostatic tissue and is responsible for cleaving pro-prostate-specific antigen into its enzymatically active form. This gene is highly expressed in prostate tumor cells and may be a prognostic maker for prostate cancer risk. Alternate splicing results in both coding and non-coding transcript variants. [provided by RefSeq, Jan 2012]
UniProt Comments for KLK2
KLK2: Glandular kallikreins cleave Met-Lys and Arg-Ser bonds in kininogen to release Lys-bradykinin. Belongs to the peptidase S1 family. Kallikrein subfamily. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Protease; EC 3.4.21.35

Chromosomal Location of Human Ortholog: 19q13.41

Cellular Component: extracellular region

Molecular Function: serine-type endopeptidase activity

Biological Process: extracellular matrix disassembly; extracellular matrix organization and biogenesis; proteolysis
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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