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anti-KLK7 antibody :: Rabbit anti-Human KLK7 Polyclonal Antibody

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Catalog # MBS855423
Unit / Price
  0.1 mg  /  $330 +1 FREE 8GB USB
Testing Data
Product Name

KLK7, Polyclonal Antibody

Also Known As

KLK7 Antibody

Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence Length
253
OMIM
604438
3D Structure
ModBase 3D Structure for P49862
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human
Form/Format
Purified by peptide affinity column containing 2% BSA and 0.02% NaN3
Preparation and Storage
Already reconstituted in 200ul sterile H2O. The antibody is stable for at least one year when stored at-20 degree C after reconstitution. Avoid repeated freeze/defrost cycles.
Other Notes
Small volumes of anti-KLK7 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-KLK7 antibody
Rabbit polyclonal KLK7 (1) antibody was raised against a peptide near intermediate residues of human KLK7.
Applications Tested/Suitable for anti-KLK7 antibody
Peptide ELISA (EIA), Western Blot (WB)
Application Notes for anti-KLK7 antibody
Peptide ELISA: 1:10,000-1:80,000
WB: 1:200-1,000

Testing Data of anti-KLK7 antibody
anti-KLK7 antibody Testing Data image
NCBI/Uniprot data below describe general gene information for KLK7. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
19,887 Da
NCBI Official Full Name
kallikrein-7 isoform 1 preproprotein
NCBI Official Synonym Full Names
kallikrein related peptidase 7
NCBI Official Symbol
NCBI Official Synonym Symbols
hK7; SCCE; PRSS6
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NCBI Protein Information
kallikrein-7
UniProt Protein Name
Kallikrein-7
UniProt Synonym Protein Names
Serine protease 6; Stratum corneum chymotryptic enzyme; hSCCE
Protein Family
UniProt Gene Name
UniProt Synonym Gene Names
PRSS6; SCCE; hK7; hSCCE  [Similar Products]
NCBI Summary for KLK7
This gene encodes a member of the kallikrein subfamily of serine proteases. These enzymes have diverse physiological functions and many kallikrein genes are biomarkers for cancer. The encoded protein has chymotrypsin-like activity and plays a role in the proteolysis of intercellular cohesive structures that precedes desquamation, the shedding of the outermost layer of the epidermis. The encoded protein may play a role in cancer invasion and metastasis, and increased expression of this gene is associated with unfavorable prognosis and progression of several types of cancer. Polymorphisms in this gene may play a role in the development of atopic dermatitis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, which is one of fifteen kallikrein subfamily members located in a gene cluster on chromosome 19. [provided by RefSeq, May 2011]
UniProt Comments for KLK7
May catalyze the degradation of intercellular cohesive structures in the cornified layer of the skin in the continuous shedding of cells from the skin surface. Specific for amino acid residues with aromatic side chains in the P1 position. Cleaves insulin A chain at '14-Tyr-|-Gln-15' and insulin B chain at '6-Leu-|-Cys-7', '16-Tyr-|-Leu-17', '25-Phe-|-Tyr-26' and '26-Tyr-|-Thr-27'. Could play a role in the activation of precursors to inflammatory cytokines.
Product References and Citations for anti-KLK7 antibody
(1) Talieri, M., Mathioudaki, K., Prezas, P., et al. Clinical significance of kallikrein-related peptidase 7 (KLK7) in colorectal cancer. Thromb. Haemost. 101 (4), 741-747 (2009).

Precautions
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Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

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