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anti-KX antibody :: Rabbit anti-Human KX / XK Polyclonal Antibody

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Catalog # MBS241098
Unit / Price DISCONTINUED
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Product Name

KX / XK, Polyclonal Antibody

Also Known As

Rabbit Polyclonal to Human KX / XK

Product Synonym Names
Anti-KX / XK Antibody (aa409-425) IHC-plus; XK; KX; Kell complex 37 kDa component; Kx antigen; MCLDS; Membrane transport protein XK; X1k; XK-related protein 1; XKR1; XRG1; Human KX; XK
Product Gene Name
Product Synonym Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence Length
444
OMIM
phenotype 314850
3D Structure
ModBase 3D Structure for P51811
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human
Specificity
Amino acids 409 to 425 of human XK
Purity/Purification
Protein G Purified
Form/Format
PBS, 0.09% sodium azide.
Concentration
1 mg/ml (lot specific)
Target Species
Human
Immunogen Description
Synthetic peptide from human XK.
Immunogen Type
Synthetic peptide
Immunogen
KX / XK antibody was raised against synthetic peptide from human XK.
Antigen Modification
aa409-425
Preparation and Storage
Long term: -20 degree C; Short term: +4 degree C. Avoid repeat freeze-thaw cycles.
Other Notes
Small volumes of anti-KX antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-KX antibody
Immunohistochemistry (IHC - Paraffin), ELISA (EIA)
Application Notes for anti-KX antibody
ELISA (1:000 - 1:1000), IHC-P (10 ug/ml)
Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antib...

Immunohistochemistry (IHC) of anti-KX antibody
Anti-XK antibody IHC of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
anti-KX antibody Immunohistochemistry (IHC) (IHC) image
Immunohistochemistry (IHC) of anti-KX antibody
Anti-XK antibody IHC of human adrenal. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
anti-KX antibody Immunohistochemistry (IHC) (IHC) image
NCBI/Uniprot data below describe general gene information for KX. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
50,902 Da
NCBI Official Full Name
membrane transport protein XK
NCBI Official Synonym Full Names
X-linked Kx blood group
NCBI Official Symbol
NCBI Official Synonym Symbols
KX; NA; NAC; X1k; XKR1; MCLDS
  [Similar Products]
NCBI Protein Information
membrane transport protein XK; Kx antigen; neurocanthocytosis; neuroacanthocytosis; XK-related protein 1; kell complex 37 kDa component; Kell blood group precursor (McLeod phenotype); XK, Kell blood group complex subunit (McLeod syndrome)
UniProt Protein Name
Membrane transport protein XK
UniProt Synonym Protein Names
Kell complex 37 kDa component; Kx antigen; XK-related protein 1
UniProt Gene Name
UniProt Synonym Gene Names
XKR1; XRG1  [Similar Products]
UniProt Entry Name
XK_HUMAN
NCBI Summary for KX
This locus controls the synthesis of the Kell blood group 'precursor substance' (Kx). Mutations in this gene have been associated with McLeod syndrome, an X-linked, recessive disorder characterized by abnormalities in the neuromuscular and hematopoietic systems. The encoded protein has structural characteristics of prokaryotic and eukaryotic membrane transport proteins. [provided by RefSeq, Jul 2008]
UniProt Comments for KX
XK: May be involved in sodium-dependent transport of neutral amino acids or oligopeptides. Defects in XK are the cause of McLeod syndrome (MLS). It is an X-linked multisystem disorder characterized by late onset abnormalities in the neuromuscular and hematopoietic systems. Belongs to the XK family.

Protein type: Cell surface; Membrane protein, integral; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: Xp21.1

Cellular Component: integral to membrane

Molecular Function: protein binding; transporter activity

Biological Process: myelination; cellular calcium ion homeostasis; transport; amino acid transport; regulation of axon diameter; skeletal muscle fiber development; regulation of cell size

Disease: Mcleod Syndrome
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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