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anti-LAMA1 antibody :: Rabbit anti-Human LAMA1 Polyclonal Antibody

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Catalog # MBS2524242
Unit / Price
  0.02 mL  /  $110 +1 FREE 8GB USB
  0.06 mL  /  $150 +1 FREE 8GB USB
  0.12 mL  /  $225 +1 FREE 8GB USB
  0.2 mL  /  $360 +1 FREE 8GB USB
Product Name

LAMA1, Polyclonal Antibody

Popular Item
Full Product Name

LAMA1 Polyclonal Antibody

Product Synonym Names
LAMA, S-LAM-alpha
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
OMIM
150320
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Purity/Purification
Antigen affinity purification
Concentration
1mg/mL (lot specific)
Preparation and Storage
Store at -20 degree C. Avoid freeze/thaw cycles
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of anti-LAMA1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-LAMA1 antibody
Background: Laminin subunit alpha-1 is a protein that in humans is encoded by the LAMA1 gene. Laminin is a complex glycoprotein, consisting of three different polypeptide chains (alpha, beta, gamma), which are bound to each other by disulfide bonds into a cross-shaped molecule comprising one long and three short arms with globules at each end. Alpha-1 is a subunit of laminin-1 (laminin-111 or EHS laminin) and laminin-3 (laminin-121 or S-laminin). Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components.
Applications Tested/Suitable for anti-LAMA1 antibody
ELISA (EIA), Immunohistochemistry (IHC)
Application Notes for anti-LAMA1 antibody
IHC: 1:25-1:100

Immunohistochemistry (IHC) of anti-LAMA1 antibody
Immunohistochemistry of paraffin-embedded Human colon cancer tissue using LAMA1 Polyclonal Antibody at dilution of 1:25
anti-LAMA1 antibody Immunohistochemistry (IHC) (IHC) image
Immunohistochemistry (IHC) of anti-LAMA1 antibody
Immunohistochemistry of paraffin-embedded Human lung cancer using LAMA1 Polyclonal Antibody at dilution of 1:25
anti-LAMA1 antibody Immunohistochemistry (IHC) (IHC) image
NCBI/Uniprot data below describe general gene information for LAMA1. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Related Accession #
NCBI Official Full Name
laminin subunit alpha-1
NCBI Official Synonym Full Names
laminin, alpha 1
NCBI Official Symbol
LAMA1  [Similar Products]
NCBI Official Synonym Symbols
LAMA; PTBHS; S-LAM-alpha
  [Similar Products]
NCBI Protein Information
laminin subunit alpha-1; S-LAM alpha; S-laminin subunit alpha; laminin A chain; laminin-3 subunit alpha
UniProt Protein Name
Laminin subunit alpha-1
UniProt Synonym Protein Names
Laminin A chain; Laminin-1 subunit alpha; Laminin-3 subunit alpha; S-laminin subunit alpha; S-LAM alpha
Protein Family
UniProt Gene Name
LAMA1  [Similar Products]
UniProt Synonym Gene Names
LAMA; S-LAM alpha  [Similar Products]
UniProt Entry Name
LAMA1_HUMAN
NCBI Summary for LAMA1
This gene encodes one of the alpha 1 subunits of laminin. The laminins are a family of extracellular matrix glycoproteins that have a heterotrimeric structure consisting of an alpha, beta and gamma chain. These proteins make up a major component of the basement membrane and have been implicated in a wide variety of biological processes including cell adhesion, differentiation, migration, signaling, neurite outgrowth and metastasis. Mutations in this gene may be associated with Poretti-Boltshauser syndrome. [provided by RefSeq, Sep 2014]
UniProt Comments for LAMA1
LAMA1: Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components.

Protein type: Extracellular matrix; Motility/polarity/chemotaxis; Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 18p11.3

Cellular Component: extracellular matrix; proteinaceous extracellular matrix; extracellular space; laminin-1 complex; laminin-3 complex; extracellular region; basement membrane; intercellular junction

Molecular Function: protein binding; extracellular matrix structural constituent; glycosphingolipid binding; receptor binding

Biological Process: regulation of cell adhesion; axon guidance; extracellular matrix organization and biogenesis; cell surface receptor linked signal transduction; regulation of embryonic development; morphogenesis of an epithelial sheet; establishment of epithelial cell polarity; cell adhesion; regulation of cell migration

Disease: Poretti-boltshauser Syndrome
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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