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anti-MAN2A1 antibody :: Rabbit anti-Human MAN2A1 Polyclonal Antibody

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Catalog # MBS7052761
Unit / Price
  0.05 mg  /  $160 +1 FREE 8GB USB
  0.1 mg  /  $235 +1 FREE 8GB USB
Product Name

MAN2A1, Polyclonal Antibody

Popular Item
Full Product Name

MAN2A1 Antibody

Product Synonym Names
Alpha-mannosidase 2; Golgi alpha-mannosidase II; AMan II; Man II; Mannosidase alpha class 2A member 1; Mannosyl-oligosaccharide 1; 3-1; 6-alpha-mannosidase; MAN2A1; MANA2
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
OMIM
U31520 mRNA
3D Structure
ModBase 3D Structure for Q16706
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Purity/Purification
>95%, Protein G purified
Form/Format
Liquid
Immunogen
Recombinant Human Alpha-mannosidase 2 protein (31-181AA)
Conjugation
Non-conjugated
Preservative
0.03% Proclin 300
Constituents
50% Glycerol, 0.01M PBS, pH 7.4
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of anti-MAN2A1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-MAN2A1 antibody
Catalyzes the first committed step in the biosynthesis of complex N-glycans. It controls conversion of high mannose to complex N-glycans; the final hydrolytic step in the N-glycan maturation pathway.
Applications Tested/Suitable for anti-MAN2A1 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
Application Notes for anti-MAN2A1 antibody
WB: 1:500-1:5000
IHC: 1:20-1:200
IF: 1:50-1:200

Western Blot (WB) of anti-MAN2A1 antibody
Western Blot
Positive WB detected in: HEK293 whole cell lysate,HepG2 whole cell lysate
All lanes: MAN2A1 antibody at 3.5ug/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 132 KDa
Observed band size: 150 KDa

anti-MAN2A1 antibody Western Blot (WB) (WB) image
Immunohistochemistry (IHC) of anti-MAN2A1 antibody
Immunohistochemistry of paraffin-embedded human lung cancer using MBS7052761 at dilution of 1:100
anti-MAN2A1 antibody Immunohistochemistry (IHC) (IHC) image
Immunohistochemistry (IHC) of anti-MAN2A1 antibody
Immunohistochemistry of paraffin-embedded human cervical cancer using MBS7052761 at dilution of 1:100
anti-MAN2A1 antibody Immunohistochemistry (IHC) (IHC) image
Immunofluorescence (IF) of anti-MAN2A1 antibody
Immunofluorescent analysis of Hela cells using MBS7052761 at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
anti-MAN2A1 antibody Immunofluorescence (IF) image
NCBI/Uniprot data below describe general gene information for MAN2A1. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
131,141 Da
NCBI Official Full Name
alpha-mannosidase 2
NCBI Official Synonym Full Names
mannosidase alpha class 2A member 1
NCBI Official Symbol
MAN2A1  [Similar Products]
NCBI Official Synonym Symbols
MANA2; MANII; GOLIM7; AMan II
  [Similar Products]
NCBI Protein Information
alpha-mannosidase 2
UniProt Protein Name
Alpha-mannosidase 2
UniProt Synonym Protein Names
Golgi alpha-mannosidase II; AMan II; Man II; Mannosidase alpha class 2A member 1; Mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase
UniProt Gene Name
MAN2A1  [Similar Products]
UniProt Synonym Gene Names
MANA2; AMan II; Man II  [Similar Products]
NCBI Summary for MAN2A1
This gene encodes a glycosyl hydrolase that localizes to the Golgi and catalyzes the final hydrolytic step in the asparagine-linked oligosaccharide (N-glycan) maturation pathway. Mutations in the mouse homolog of this gene have been shown to cause a systemic autoimmune disease similar to human systemic lupus erythematosus. [provided by RefSeq, Dec 2013]
UniProt Comments for MAN2A1
MAN2A1: Catalyzes the first committed step in the biosynthesis of complex N-glycans. It controls conversion of high mannose to complex N-glycans; the final hydrolytic step in the N-glycan maturation pathway. Belongs to the glycosyl hydrolase 38 family.

Protein type: EC 3.2.1.114; Glycan Metabolism - N-glycan biosynthesis; Hydrolase; Membrane protein, integral

Chromosomal Location of Human Ortholog: 5q21.3

Cellular Component: Golgi membrane; membrane

Molecular Function: mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity

Biological Process: mannose metabolic process; N-glycan processing; protein deglycosylation
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Products associated withanti-MAN2A1 antibody
 Reference Product  PubMed Publications
 MGAT1 antibody  >1 publications with MAN2A1 and MGAT1
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