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anti-MYCBP antibody :: Rabbit anti-Human MYCBP Polyclonal Antibody

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Catalog # MBS129245
Unit / Price
  0.05 mL  /  $230 +1 FREE 8GB USB
  0.1 mL  /  $305 +1 FREE 8GB USB
  0.2 mL  /  $460 +1 FREE 8GB USB
Western Blot (WB)
Product Name

MYCBP, Polyclonal Antibody

Full Product Name

MYCBP Polyclonal Antibody

Product Synonym Names
AMY-1
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
OMIM
606535
3D Structure
ModBase 3D Structure for Q99417
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Purity/Purification
Affinity Purification
Concentration
1mg/ml (lot specific)
Species
Human
Immunogen
Recombinant Protein
Immunogen
Recombinant protein of human MYCBP
Calculated Molecular Weight
12kDa
Preparation and Storage
Store at -20 degree C (regular) or -80 degree C (long term). Avoid freeze / thaw cycles.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Other Notes
Small volumes of anti-MYCBP antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-MYCBP antibody
The protein encoded by this gene binds to the N-terminus of the oncogenic protein C-MYC, enhancing the ability of C-MYC to activate E box-dependent transcription. The encoded protein is normally found in the cytoplasm, but it translocates to the nucleus during S phase of the cell cycle and associates with C-MYC. This protein may be involved in spermatogenesis. This gene can be silenced by microRNA-22. Two transcript variants, one protein-coding and the other probably not protein-coding, have been found for this gene.
Product Categories/Family for anti-MYCBP antibody
Applications Tested/Suitable for anti-MYCBP antibody
Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
Application Notes for anti-MYCBP antibody
WB: 1:500-1:2000
IHC: 1:50-1:200
IF: 1:50-1:200

Western Blot (WB) of anti-MYCBP antibody
Western blot analysis of extracts of various cell lines, using MYCBP antibody at 1:3000 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (MBS128200) at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Enhanced Kit.
Exposure time: 90s.
anti-MYCBP antibody Western Blot (WB) (WB) image
NCBI/Uniprot data below describe general gene information for MYCBP. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
103
NCBI Official Full Name
C-Myc-binding protein
NCBI Official Synonym Full Names
MYC binding protein
NCBI Official Symbol
MYCBP  [Similar Products]
NCBI Official Synonym Symbols
AMY-1
  [Similar Products]
NCBI Protein Information
C-Myc-binding protein; associate of myc-1; c-myc binding protein
UniProt Protein Name
C-Myc-binding protein
UniProt Synonym Protein Names
Associate of Myc 1; AMY-1
Protein Family
UniProt Gene Name
MYCBP  [Similar Products]
UniProt Synonym Gene Names
AMY1; AMY-1  [Similar Products]
UniProt Entry Name
MYCBP_HUMAN
NCBI Summary for MYCBP
The protein encoded by this gene binds to the N-terminus of the oncogenic protein C-MYC, enhancing the ability of C-MYC to activate E box-dependent transcription. The encoded protein is normally found in the cytoplasm, but it translocates to the nucleus during S phase of the cell cycle and associates with C-MYC. This protein may be involved in spermatogenesis. This gene can be silenced by microRNA-22. Two transcript variants, one protein-coding and the other probably not protein-coding, have been found for this gene. [provided by RefSeq, Nov 2011]
UniProt Comments for MYCBP
MYCBP: May control the transcriptional activity of MYC. Stimulates the activation of E box-dependent transcription by MYC. Belongs to the AMY1 family.

Protein type: Transcription, coactivator/corepressor

Chromosomal Location of Human Ortholog: 1p33-p32.2

Cellular Component: centrosome; mitochondrion; cytoplasm; nucleus

Molecular Function: protein binding; transcription coactivator activity

Biological Process: transcription, DNA-dependent; regulation of transcription, DNA-dependent; spermatogenesis
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Pathways associated with anti-MYCBP antibody
 Products by Pathway  Pathway Diagram
 Notch Signaling Pathway antibodies  Notch Signaling Pathway Diagram
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