• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

anti-NAB2 antibody :: Rabbit anti-Human NAB2 Polyclonal Antibody

Scan QR to view Datasheet
Catalog # MBS1497428
Unit / Price
Scan QR to view Datasheet
  0.05 mL  /  $120 +1 FREE 8GB USB
  0.1 mL  /  $160 +1 FREE 8GB USB
Product Name

NAB2, Polyclonal Antibody

Popular Item
Full Product Name

NAB2 Antibody

Product Synonym Names
EGR-1-binding protein 2; Melanoma-associated delayed early response protein; Protein MADER; NAB2; MADER
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
OMIM
602381
3D Structure
ModBase 3D Structure for Q15742
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Purity/Purification
Antigen Affinity Purified
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Conjugate
Non-conjugated
Immunogen
Recombinant human NGFI-A-binding protein 2 protein (1-200aa)
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-12153 / sc-12151 / sc-22815
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of anti-NAB2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-NAB2 antibody
Acts as a transcriptional repressor for zinc finger transcription factors EGR1 and EGR2. Isoform 2 lacks repression ability.
Applications Tested/Suitable for anti-NAB2 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-NAB2 antibody
Recommended dilution: WB:1:200-1000
IHC:1:20-1:200

Western Blot (WB) of anti-NAB2 antibody
Western blot
All lanes: NAB2 antibody at 3ug/ml+Hela whole cell lysate
Secondary
Goat polyclonal to rabbit at 1/10000 dilution
Predicted band size: 57,35,50 kDa
Observed band size: 57 kDa

anti-NAB2 antibody Western Blot (WB) (WB) image
Immunohistochemistry (IHC) of anti-NAB2 antibody
Immunohistochemistry of paraffin-embedded human tonsil using MBS1497428 at dilution 1:100
anti-NAB2 antibody Immunohistochemistry (IHC) (IHC) image
Immunohistochemistry (IHC) of anti-NAB2 antibody
Immunohistochemistry of paraffin-embedded human placenta using MBS1497428 at dilution 1:100
anti-NAB2 antibody Immunohistochemistry (IHC) (IHC) image
NCBI/Uniprot data below describe general gene information for NAB2. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
49,748 Da
NCBI Official Full Name
NGFI-A-binding protein 2
NCBI Official Synonym Full Names
NGFI-A binding protein 2 (EGR1 binding protein 2)
NCBI Official Symbol
NCBI Official Synonym Symbols
MADER
  [Similar Products]
NCBI Protein Information
NGFI-A-binding protein 2
UniProt Protein Name
NGFI-A-binding protein 2
UniProt Synonym Protein Names
EGR-1-binding protein 2; Melanoma-associated delayed early response protein; Protein MADER
Protein Family
UniProt Gene Name
UniProt Synonym Gene Names
MADER; Protein MADER  [Similar Products]
UniProt Entry Name
NAB2_HUMAN
NCBI Summary for NAB2
This gene encodes a member of the family of NGFI-A binding (NAB) proteins, which function in the nucleus to repress transcription induced by some members of the EGR (early growth response) family of transactivators. NAB proteins can homo- or hetero-multimerize with other EGR or NAB proteins through a conserved N-terminal domain, and repress transcription through two partially redundant C-terminal domains. Transcriptional repression by the encoded protein is mediated in part by interactions with the nucleosome remodeling and deactylase (NuRD) complex. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq, Jul 2008]
UniProt Comments for NAB2
NAB2: Acts as a transcriptional repressor for zinc finger transcription factors EGR1 and EGR2. Isoform 2 lacks repression ability. Belongs to the NAB family. 3 isoforms of the human protein are produced by alternative splicing.

Chromosomal Location of Human Ortholog: 12q13.3

Cellular Component: nucleus

Molecular Function: protein binding; transcription corepressor activity; transcription factor binding

Biological Process: cell proliferation; endochondral ossification; myelination; negative regulation of transcription from RNA polymerase III promoter; nervous system development; regulation of epidermis development; Schwann cell differentiation; transcription, DNA-dependent
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000