NP_005960.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Related Accession #
Molecular Weight
42,823 Da
NCBI Official Full Name
nucleosome assembly protein 1-like 4
NCBI Official Synonym Full Names
nucleosome assembly protein 1-like 4
NCBI Protein Information
nucleosome assembly protein 1-like 4; NAP-2; nucleosome assembly protein 2; nucleosome assembly protein 1-like 4b
UniProt Protein Name
Nucleosome assembly protein 1-like 4
UniProt Synonym Protein Names
Nucleosome assembly protein 2
UniProt Synonym Gene Names
UniProt Entry Name
NP1L4_HUMAN
NCBI Summary for NAP-2
This gene encodes a member of the nucleosome assembly protein (NAP) family which can interact with both core and linker histones. It can shuttle between the cytoplasm and nucleus, suggesting a role as a histone chaperone. This gene is one of several located near the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer. [provided by RefSeq, Jul 2008]
UniProt Comments for NAP-2
Subcellular location: Nucleus.
Tissue specificity: Ubiquitous. Biallelically expressed in fetal and adult tissues. Highest levels in testis.
Post-translational modification: Polyglutamylated by TTLL4, a modification that occurs exclusively on glutamate residues and results in polyglutamate chains on the gamma-carboxyl group. Some residues may also be monoglycylated but not polyglycylated due to the absence of functional TTLL10 in human
By similarity.
Sequence similarities: Belongs to the nucleosome assembly protein (NAP) family.
Research Articles on NAP-2
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Products associated with anti-NAP-2 antibody
Diseases associated with anti-NAP-2 antibody
Organs/Tissues associated with anti-NAP-2 antibody
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