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anti-NUDT11 antibody :: Rabbit anti-Human NUDT11 Polyclonal Antibody

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Catalog # MBS1494657
Unit / Price
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  0.05 mg  /  $160 +1 FREE 8GB USB
  0.1 mg  /  $235 +1 FREE 8GB USB
Product Name

NUDT11, Polyclonal Antibody

Popular Item
Full Product Name

NUDT11 Antibody

Product Synonym Names
Diphosphoinositol polyphosphate phosphohydrolase 3-beta (EC:3.6.1.52); DIPP-3-beta; DIPP3-beta; hDIPP3beta; NUDT11; APS1; DIPP3B; Diadenosine 5'; 5'''-P1; P6-hexaphosphate hydrolase 3-beta; Diadenosine hexaphosphate hydrolase (AMP-forming) (EC:3.6.1.60); Nucleoside diphosphate-linked moiety X motif 11; Nudix motif 11; hAps1
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
OMIM
300528
3D Structure
ModBase 3D Structure for Q96G61
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Purity/Purification
>95%, Protein G Purified
Storage Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Conjugate
Non-conjugated
Immunogen
Recombinant human Diphosphoinositol polyphosphate phosphohydrolase 3-beta protein
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of anti-NUDT11 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-NUDT11 antibody
Cleaves a beta-phosphate from the diphosphate groups in PP-InsP5 (diphosphoinositol pentakisphosphate), suggesting that it may play a role in signal transduction. Also able to catalyze the hydrolysis of dinucleoside oligophosphates, with Ap6A and Ap5A being the preferred substrates. The major reaction products are ADP and p4a from Ap6A and ADP and ATP from Ap5A. Also able to hydrolyze 5-phosphoribose 1-diphosphate.
Applications Tested/Suitable for anti-NUDT11 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-NUDT11 antibody
Recommended dilution: WB:1:500-2000
IHC:1:20-1:200

Western Blot (WB) of anti-NUDT11 antibody
Western blot
All lanes: NUDT11 antibody at 2ug/ml+ U251 whole cell lysate
Goat polyclonal to rabbit at 1/10000 dilution
Predicted band size: 19 kDa
Observed band size: 19 kDa

anti-NUDT11 antibody Western Blot (WB) (WB) image
Immunohistochemistry (IHC) of anti-NUDT11 antibody
Immunohistochemistry of paraffin-embedded human testis tissue using MBS1494657 at dilution of 1:100
anti-NUDT11 antibody Immunohistochemistry (IHC) (IHC) image
NCBI/Uniprot data below describe general gene information for NUDT11. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
18,559 Da
NCBI Official Full Name
diphosphoinositol polyphosphate phosphohydrolase 3-beta
NCBI Official Synonym Full Names
nudix hydrolase 11
NCBI Official Symbol
NUDT11  [Similar Products]
NCBI Official Synonym Symbols
APS1; ASP1; DIPP3b; DIPP3beta; hDIPP3beta
  [Similar Products]
NCBI Protein Information
diphosphoinositol polyphosphate phosphohydrolase 3-beta
UniProt Protein Name
Diphosphoinositol polyphosphate phosphohydrolase 3-beta
UniProt Synonym Protein Names
Diadenosine 5',5'''-P1,P6-hexaphosphate hydrolase 3-beta; Diadenosine hexaphosphate hydrolase (AMP-forming) (EC:3.6.1.60
Protein Family
UniProt Gene Name
NUDT11  [Similar Products]
UniProt Synonym Gene Names
APS1; DIPP3B; Nudix motif 11  [Similar Products]
UniProt Entry Name
NUD11_HUMAN
NCBI Summary for NUDT11
NUDT11 belongs to a subgroup of phosphohydrolases that preferentially attack diphosphoinositol polyphosphates (Hidaka et al., 2002 [PubMed 12105228]).[supplied by OMIM, Mar 2008]
UniProt Comments for NUDT11
NUDT11: Cleaves a beta-phosphate from the diphosphate groups in PP-InsP5 (diphosphoinositol pentakisphosphate), suggesting that it may play a role in signal transduction. Also able to catalyze the hydrolysis of dinucleoside oligophosphates, with Ap6A and Ap5A being the preferred substrates. The major reaction products are ADP and p4a from Ap6A and ADP and ATP from Ap5A. Also able to hydrolyze 5-phosphoribose 1-diphosphate. Belongs to the Nudix hydrolase family. DIPP subfamily.

Protein type: EC 3.6.1.52; Hydrolase; EC 3.6.1.60

Chromosomal Location of Human Ortholog: Xp11.22

Cellular Component: cytosol; intracellular

Molecular Function: diphosphoinositol-polyphosphate diphosphatase activity; metal ion binding

Biological Process: inositol phosphate metabolic process
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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