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anti-NUDT16 antibody :: Rabbit NUDT16 Polyclonal Antibody

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Catalog # MBS839126
Unit / Price
  0.05 mL  /  $490 +1 FREE 8GB USB
anti-NUDT16 antibody
Product Name

NUDT16, Polyclonal Antibody

Popular Item
Full Product Name

NUDT16 antibody

Product Synonym Names
Polyclonal NUDT16; Anti-NUDT16; Nudix Type Motif 16; Nudt16; Flj31265
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human. Other species are not tested.
Purity/Purification
NUDT16 antibody was purified by Antigen Affinity chromatography
Form/Format
Liquid in PBS, pH 7.3, with 0.02% NaN3 and 50% glycerol.
Concentration
0.34mg/ml (lot specific)
Biological Significance
NUDT16 is an RNA-binding and decapping enzyme that catalyzes the cleavage of the cap structure of snoRNAs and mRNAs in a metal-dependent manner.
Immunogen
NUDT16 antibody was raised in Rabbit using Human NUDT16 as the immunogen
Preparation and Storage
4°C for shipping. Upon receipt store at -20°C to -80°C . Avoid repeat freeze-thaw cycles.
Other Notes
Small volumes of anti-NUDT16 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-NUDT16 antibody
Rabbit polyclonal NUDT16 antibody
Applications Tested/Suitable for anti-NUDT16 antibody
ELISA (EIA), Western Blot (WB)
Application Notes for anti-NUDT16 antibody
WB: 1:1,000-10,000
IP: 1:500-1:5,000
IHC and IF: 1:20-1:200
NCBI/Uniprot data below describe general gene information for NUDT16. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
NUDT16 protein
NCBI Official Synonym Full Names
nudix (nucleoside diphosphate linked moiety X)-type motif 16
NCBI Official Symbol
NUDT16  [Similar Products]
NCBI Protein Information
U8 snoRNA-decapping enzyme
UniProt Protein Name
U8 snoRNA-decapping enzyme
UniProt Synonym Protein Names
IDP phosphatase (EC:3.6.1.-); IDPase; Inosine diphosphate phosphatase; Nucleoside diphosphate-linked moiety X motif 16; Nudix motif 16; U8 snoRNA-binding protein H29K; m7GpppN-mRNA hydrolase
Protein Family
UniProt Gene Name
NUDT16  [Similar Products]
UniProt Synonym Gene Names
IDPase; Nudix motif 16  [Similar Products]
UniProt Entry Name
NUD16_HUMAN
UniProt Comments for NUDT16
NUDT16: RNA-decapping enzyme that binds specifically to U8 snoRNA. Part of the U8 snoRNP complex that is required for the accumulation of mature 5.8S and 28S rRNA. Has diphosphatase activity and removes m7G and m227G caps from U8 snoRNA. Has broad substrate specificity with manganese or cobalt as cofactor and can act on various RNA species (in vitro). Belongs to the Nudix hydrolase family.

Protein type: EC 3.6.1.62; Nucleolus; Hydrolase

Chromosomal Location of Human Ortholog: 3q22.1

Cellular Component: nucleoplasm; cytoplasm; nucleolus; nucleus

Molecular Function: mRNA binding; snoRNA binding; m7G(5')pppN diphosphatase activity; protein homodimerization activity; metalloexopeptidase activity; GTP binding; manganese ion binding; magnesium ion binding; cobalt ion binding

Biological Process: snoRNA catabolic process; dephosphorylation; nucleobase, nucleoside and nucleotide metabolic process; positive regulation of cell proliferation; mRNA catabolic process; proteolysis; adenosine to inosine editing; IDP catabolic process
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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