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anti-p47-phox antibody :: Rabbit anti-Human p47 phox Polyclonal Antibody

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Catalog # MBS9503394
Unit / Price
  0.05 mg  /  $225 +1 FREE 8GB USB
  0.1 mg  /  $310 +1 FREE 8GB USB
Product Name

p47 phox (p47-phox), Polyclonal Antibody

Popular Item
Full Product Name

p47 phox (Phospho-Ser345) Antibody

Product Synonym Names
47 kDa autosomal chronic granulomatous disease protein; 47 kDa neutrophil oxidase factor; NCF-1; NCF-47K; NCF1; Neutrophil cytosol factor 1; Neutrophil cytosolic factor 1; Neutrophil NADPH oxidase factor 1; P47 phox
Product Synonym Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
OMIM
M25665 mRNA
3D Structure
ModBase 3D Structure for P14598
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human
Specificity
p47 phox (Phospho-Ser345) Antibody detects endogenous levels of p47 phox only when phosphorylated at Ser345.
Purity/Purification
Purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.
Form/Format
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1 mg/ml (lot specific)
Target Modification
Phospho
Modification Sites
H:S345
Immunogen
The antiserum was produced against synthesized peptide derived from human p47 phox around the phosphorylation site of Ser345.
Immunogen Range
311-360
Preparation and Storage
Stable at -20 degree C for at least 1 year.
Other Notes
Small volumes of anti-p47-phox antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-p47-phox antibody
Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA)
Application Notes for anti-p47-phox antibody
WB: 1:500~1:1000
IHC: 1:50~1:100
ELISA: 1:1000

Immunohistochemistry (IHC) of anti-p47-phox antibody
Immunohistochemistry analysis of paraffin-embedded human brain, using p47 phox (Phospho-Ser345) Antibody. The picture on the right is blocked with the phospho peptide.
anti-p47-phox antibody Immunohistochemistry (IHC) (IHC) image
Western Blot (WB) of anti-p47-phox antibody
Western blot analysis of lysates from HepG2 cells treated with TNF 20ng/ml 5', using p47 phox (Phospho-Ser345) Antibody. The lane on the right is blocked with the phospho peptide.
anti-p47-phox antibody Western Blot (WB) (WB) image
NCBI/Uniprot data below describe general gene information for p47-phox. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
44 kDa
NCBI Official Full Name
neutrophil cytosol factor 1
NCBI Official Synonym Full Names
neutrophil cytosolic factor 1
NCBI Official Symbol
NCBI Official Synonym Symbols
NCF1A; NOXO2; p47phox; SH3PXD1A
  [Similar Products]
NCBI Protein Information
neutrophil cytosol factor 1
UniProt Protein Name
Neutrophil cytosol factor 1
UniProt Synonym Protein Names
47 kDa autosomal chronic granulomatous disease protein; 47 kDa neutrophil oxidase factor; NCF-47K; Neutrophil NADPH oxidase factor 1; Nox organizer 2; Nox-organizing protein 2; SH3 and PX domain-containing protein 1A; p47-phox
UniProt Gene Name
UniProt Synonym Gene Names
NOXO2; SH3PXD1A; NCF-1  [Similar Products]
NCBI Summary for p47-phox
The protein encoded by this gene is a 47 kDa cytosolic subunit of neutrophil NADPH oxidase. This oxidase is a multicomponent enzyme that is activated to produce superoxide anion. Mutations in this gene have been associated with chronic granulomatous disease. [provided by RefSeq, Jul 2008]
UniProt Comments for p47-phox
NCF2, NCF1, and a membrane bound cytochrome b558 are required for activation of the latent NADPH oxidase (necessary for superoxide production).
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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