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anti-PKG2 antibody :: Rabbit anti-Human PKG2 Polyclonal Antibody

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Catalog # MBS9408757
Unit / Price
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  0.05 mL  /  $200 +1 FREE 8GB USB
  0.1 mL  /  $255 +1 FREE 8GB USB
Western Blot (WB)
Product Name

PKG2, Polyclonal Antibody

Popular Item
Full Product Name

PKG2 (Ab-126) Antibody

Product Synonym Names
CGK 2; cGKII; cGMP-dependent protein kinase 2; EC 2.7.11.12; KGP2
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
OMIM
601591
3D Structure
ModBase 3D Structure for Q13237
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human
Specificity
The antibody detects endogenous levels of total PKG2 protein.
Purity/Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form/Format
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1.0 mg/ml (lot specific)
Immunogen Type
Peptide
Immunogen Description
Synthesized non-phosphopeptide derived from human PKG2 around the phosphorylation site of serine 126 (G-V-S(p)-A-E).
SDS-PAGE
87 kD
Target Name
PKG2
Preparation and Storage
Store at -20°C
Other Notes
Small volumes of anti-PKG2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-PKG2 antibody
This gene encodes a protein that belongs to the serine/threonine protein kinase family of proteins. The encoded protein plays a role in the regulation of fluid balance in the intestine. A similar protein in mouse is thought to regulate differentiation and proliferation of cells in the colon. Alternate splicing results in multiple transcript variants.Orstavik S., Biochem. Biophys. Res. Commun. 220:759-765(1996).Fujii M., FEBS Lett. 375:263-267(1995).Witczak O., Biochem. Biophys. Res. Commun. 245:113-119(1998).
Product Categories/Family for anti-PKG2 antibody
Applications Tested/Suitable for anti-PKG2 antibody
Western Blot (WB)
Application Notes for anti-PKG2 antibody
Western blotting: 1:500~1:3000

Western Blot (WB) of anti-PKG2 antibody
Western blot analysis of extracts from 293 cells, treated with anisomycin (25ug/ml, 30mins), using PKG2 (Ab-126) antibody.
anti-PKG2 antibody Western Blot (WB) (WB) image
NCBI/Uniprot data below describe general gene information for PKG2. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
84,398 Da
NCBI Official Full Name
cGMP-dependent protein kinase 2 isoform b
NCBI Official Synonym Full Names
protein kinase, cGMP-dependent, type II
NCBI Official Symbol
PRKG2  [Similar Products]
NCBI Official Synonym Symbols
cGK2; cGKII; PRKGR2
  [Similar Products]
NCBI Protein Information
cGMP-dependent protein kinase 2
UniProt Protein Name
cGMP-dependent protein kinase 2
UniProt Synonym Protein Names
cGMP-dependent protein kinase II; cGKII
UniProt Gene Name
PRKG2  [Similar Products]
UniProt Synonym Gene Names
PRKGR2; cGK 2; cGK2; cGKII  [Similar Products]
UniProt Entry Name
KGP2_HUMAN
NCBI Summary for PKG2
This gene encodes a protein that belongs to the serine/threonine protein kinase family of proteins. The encoded protein plays a role in the regulation of fluid balance in the intestine. A similar protein in mouse is thought to regulate differentiation and proliferation of cells in the colon. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]
UniProt Comments for PKG2
PKG2: an AGC kinase of the PKG family. Type II cGMP-dependent protein kinase is expressed at high levels in brain, lung and intestinal mucosa.

Protein type: Protein kinase, Ser/Thr (non-receptor); EC 2.7.11.12; Protein kinase, AGC; Kinase, protein; AGC group; PKG family

Chromosomal Location of Human Ortholog: 4q13.1-q21.1

Cellular Component: nuclear membrane; apical plasma membrane; cytosol

Molecular Function: protein homodimerization activity; cGMP-dependent protein kinase activity; cGMP binding; ATP binding; protein kinase activity

Biological Process: regulation of nitric-oxide synthase activity; circadian regulation of gene expression; blood coagulation; signal transduction; nitric oxide metabolic process; protein amino acid phosphorylation
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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