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anti-PLIN3 antibody :: Rabbit anti-Human PLIN3 Polyclonal Antibody

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Catalog # MBS129821 (SPECIAL PROMOTION: Get FREE $5 Starbucks gift card (Maximum 5 gift cards/product). Gift card(s) will be included with shipment)
Unit / Price
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  0.1 mL  /  $275 +1 FREE 8GB USB
  0.2 mL  /  $430 +1 FREE 8GB USB
Western Blot (WB)
Product Name

PLIN3, Polyclonal Antibody

Popular Item
Full Product Name

PLIN3 Polyclonal Antibody

Product Synonym Names
TIP47: PP17; TIP47; M6PRBP1
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
OMIM
602702
3D Structure
ModBase 3D Structure for O60664
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Purity/Purification
Affinity Purification
Source
Rabbit
Buffer
PBS with 0.02 % sodium azide,pH 7.3.
Immunogen
A synthetic peptide of human PLIN3
Calculated Molecular Weight
28 kDa/45kDa/46 kDa/47kDa
Observed MW
50kDa
Preparation and Storage
Store at 4°C.
Avoid freeze/ thaw cycles.
Other Notes
Small volumes of anti-PLIN3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-PLIN3 antibody
Mannose 6-phophate receptors (MPRs) deliver lysosomal hydrolase from the Golgi to endosomes and then return to the Golgi complex. The protein encoded by this gene interacts with the cytoplasmic domains of both cation-independent and cation-dependent MPRs, and is required for endosome-to-Golgi transport. This protein also binds directly to the GTPase RAB9 (RAB9A), a member of the RAS oncogene family. The interaction with RAB9 has been shown to increase the affinity of this protein for its cargo. Multiple transcript variants encoding different isoforms have been found for this gene.
Product Categories/Family for anti-PLIN3 antibody
Applications Tested/Suitable for anti-PLIN3 antibody
Western Blot (WB)
Application Notes for anti-PLIN3 antibody
WB: 1:500 - 1:2000

Western Blot (WB) of anti-PLIN3 antibody
Western blot analysis of extracts of K562 cells, using PLIN3 antibody.
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (MBS128200) at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
anti-PLIN3 antibody Western Blot (WB) (WB) image
NCBI/Uniprot data below describe general gene information for PLIN3. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
Perilipin-3
NCBI Official Synonym Full Names
perilipin 3
NCBI Official Symbol
PLIN3  [Similar Products]
NCBI Official Synonym Symbols
PP17; TIP47; M6PRBP1
  [Similar Products]
NCBI Protein Information
perilipin-3; placental protein 17; 47 kDa MPR-binding protein; cargo selection protein TIP47; tail-interacting protein, 47 kD; mannose-6-phosphate receptor-binding protein 1
UniProt Protein Name
Perilipin-3
UniProt Synonym Protein Names
47 kDa mannose 6-phosphate receptor-binding protein; 47 kDa MPR-binding protein; Cargo selection protein TIP47; Mannose-6-phosphate receptor-binding protein 1; Placental protein 17; PP17
Protein Family
UniProt Gene Name
PLIN3  [Similar Products]
UniProt Synonym Gene Names
M6PRBP1; TIP47; 47 kDa MPR-binding protein; PP17  [Similar Products]
UniProt Entry Name
PLIN3_HUMAN
NCBI Summary for PLIN3
Mannose 6-phophate receptors (MPRs) deliver lysosomal hydrolase from the Golgi to endosomes and then return to the Golgi complex. The protein encoded by this gene interacts with the cytoplasmic domains of both cation-independent and cation-dependent MPRs, and is required for endosome-to-Golgi transport. This protein also binds directly to the GTPase RAB9 (RAB9A), a member of the RAS oncogene family. The interaction with RAB9 has been shown to increase the affinity of this protein for its cargo. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Aug 2009]
UniProt Comments for PLIN3
perilipin 3: a membrane-associated protein and a coat protein for lipid droplets (LDs). It has been described as a mannose-6-phosphate receptor (MPR) binding protein required for endosome-to-Golgi transport of MPRs, but this function has been disputed. Interacts with M6PR and IGF2R via their cytoplasmic domains. Affects hepatic lipid and glucose metabolism. Belongs to the perilipin family. 3 isoforms of the human protein are produced by alternative splicing. Isoform 2 may exist as a homodimer known as PP17C.

Protein type: Vesicle

Chromosomal Location of Human Ortholog: 19p13.3

Cellular Component: Golgi apparatus; intracellular membrane-bound organelle; membrane; cytoplasm; lipid particle; endosome membrane; endosome

Molecular Function: protein binding

Biological Process: vesicle-mediated transport
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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