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anti-PPP1R3C antibody :: Rabbit anti-Human PPP1R3C Polyclonal Antibody

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Catalog # MBS417737
Unit / Price
  0.1 mg  /  $230 +1 FREE 8GB USB
Testing Data
Product Name

PPP1R3C, Polyclonal Antibody

Popular Item
Also Known As

Anti-PPP1R3C Antibody

Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence Length
317
OMIM
602999
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human
Purity/Purification
Affinity purified
Form/Format
Liquid
Concentration
100ug/100ul (lot specific)
Storage Buffer
PBS, pH 7.4 with 0.02% sodium azide.
Immunogen
Rabbit polyclonal PPP1R3C antibody was raised against a recombinant human PPP1R3C protein 79- 295aa (BC012625).
Preparation and Storage
This product is stable for several weeks at 4 degree C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20 degree C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.
Other Notes
Small volumes of anti-PPP1R3C antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-PPP1R3C antibody
This gene encodes a regulatory subunit of protein phosphatase-1 (PP1). PP1 catalyzes reversible protein phosphorylation, which is important in a wide range of cellular activities: neuronal, muscular, RNA splicing, protein synthesis, cell death, and glycogen metabolism, to name just a few. By interacting with different regulatory subunits, PP1 is directed to different parts of the cell, to different substrates, or to respond to extracellular signals. [provided by RefSeq, Oct 2011]
Applications Tested/Suitable for anti-PPP1R3C antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-PPP1R3C antibody
ELISA titer: 1:20,000-1:80,000
Western blot analysis: 1:200-1:1,000
Immunohistochemistry: 1:100-1:500
Optimal dilutions/concentrations should be determined by the end user

Testing Data of anti-PPP1R3C antibody
anti-PPP1R3C antibody Testing Data image
NCBI/Uniprot data below describe general gene information for PPP1R3C. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
36,445 Da
NCBI Official Full Name
protein phosphatase 1 regulatory subunit 3C
NCBI Official Synonym Full Names
protein phosphatase 1, regulatory subunit 3C
NCBI Official Symbol
PPP1R3C  [Similar Products]
NCBI Official Synonym Symbols
PPP1R5
  [Similar Products]
NCBI Protein Information
protein phosphatase 1 regulatory subunit 3C; PP1 subunit R5; PPP1R3C; PTG; Phosphatase 1, regulatory inhibitor subunit 5; protein phosphatase 1 regulatory subunit 5; protein phosphatase 1, regulatory (inhibitor) subunit 3C; protein targeting to glycogen
UniProt Protein Name
Protein phosphatase 1 regulatory subunit 3C
UniProt Synonym Protein Names
Protein phosphatase 1 regulatory subunit 5; PP1 subunit R5; Protein targeting to glycogen; PTG
UniProt Gene Name
PPP1R3C  [Similar Products]
UniProt Entry Name
PPR3C_HUMAN
NCBI Summary for PPP1R3C
This gene encodes a regulatory subunit of protein phosphatase-1 (PP1). PP1 catalyzes reversible protein phosphorylation, which is important in a wide range of cellular activities: neuronal, muscular, RNA splicing, protein synthesis, cell death, and glycogen metabolism, to name just a few. By interacting with different regulatory subunits, PP1 is directed to different parts of the cell, to different substrates, or to respond to extracellular signals. [provided by RefSeq, Oct 2011]
UniProt Comments for PPP1R3C
PPP1R3C: Acts as a glycogen-targeting subunit for PP1 and regulates its activity. Activates glycogen synthase, reduces glycogen phosphorylase activity and limits glycogen breakdown. Dramatically increases basal and insulin-stimulated glycogen synthesis upon overexpression in a variety of cell types.

Protein type: Motility/polarity/chemotaxis; Protein phosphatase, regulatory subunit

Chromosomal Location of Human Ortholog: 10q23-q24

Cellular Component: cytosol

Molecular Function: protein binding; protein serine/threonine phosphatase activity; protein phosphatase binding

Biological Process: glycogen biosynthetic process; dephosphorylation; carbohydrate metabolic process; glucose metabolic process; pathogenesis
Product References and Citations for anti-PPP1R3C antibody
(1) Guerrero,R., Vernia,S., Sanz,R. et al. APTG variant contributes to a milder phenotypein Lafora disease. PLoS ONE 6 (6), E21294(2011)

Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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