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anti-PTPRS antibody :: Chicken anti-Human Protein Tyrosine Phosphatase, Receptor Type sigma Polyclonal Antibody

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Catalog # MBS621163
Unit / Price
  0.05 mg  /  $540 +1 FREE 8GB USB
anti-PTPRS antibody
Product Name

Protein Tyrosine Phosphatase, Receptor Type sigma (PTPRS), Polyclonal Antibody

Also Known As

Protein Tyrosine Phosphatase, Receptor Type sigma (PTPRS)

Product Synonym Names
Anti -Protein Tyrosine Phosphatase, Receptor Type sigma (PTPRS)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Chromosome Location
chromosome: 19; Location: 19p13.3
3D Structure
ModBase 3D Structure for Q59FX6
Clonality
Polyclonal
Isotype
IgY
Host
Chicken
Species Reactivity
Human
Specificity
Recognizes human Protein Tyrosine Phosphatase, Receptor Type sigma.
Purity/Purification
Affinity Purified
Purified by immunoaffinity chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Glycerol free.
Immunogen
Synthetic peptide corresponding to aa330-524
Preparation and Storage
May be stored at 4 degree C for short-term only. For long-term storage, store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Other Notes
Small volumes of anti-PTPRS antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-PTPRS antibody
This protein is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular region, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. The extracellular region of this protein is composed of multiple Ig-like and fibronectin type III-like domains. Studies of the similar gene in mice suggested that this PTP may be involved in cell-cell interaction, primary axonogenesis, and axon guidance during embryogenesis. This PTP has been also implicated in the molecular control of adult nerve repair.
Applications Tested/Suitable for anti-PTPRS antibody
ELISA (EL/EIA), Western Blot (WB)
Application Notes for anti-PTPRS antibody
Suitable for use in ELISA and Western Blot.
Dilution: Western Blot: 1:500-1:1000
NCBI/Uniprot data below describe general gene information for PTPRS. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
UniProt Primary Accession #
UniProt Related Accession #
Molecular Weight
174,656 Da[Similar Products]
NCBI Official Full Name
protein tyrosine phosphatase, receptor type, sigma isoform 3 variant
NCBI Official Synonym Full Names
protein tyrosine phosphatase, receptor type, S
NCBI Official Symbol
PTPRS  [Similar Products]
NCBI Official Synonym Symbols
PTPSIGMA; PTPRS
  [Similar Products]
NCBI Protein Information
receptor-type tyrosine-protein phosphatase S; R-PTP-S; R-PTP-sigma; protein tyrosine phosphatase PTPsigma; receptor-type tyrosine-protein phosphatase sigma; protein tyrosine phosphatase, receptor type, sigma
UniProt Protein Name
Protein tyrosine phosphatase, receptor type, sigma isoform 3 variant
UniProt Entry Name
Q59FX6_HUMAN
NCBI Summary for PTPRS
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular region, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. The extracellular region of this protein is composed of multiple Ig-like and fibronectin type III-like domains. Studies of the similar gene in mice suggested that this PTP may be involved in cell-cell interaction, primary axonogenesis, and axon guidance during embryogenesis. This PTP has been also implicated in the molecular control of adult nerve repair. Four alternatively spliced transcript variants, which encode distinct proteins, have been reported. [provided by RefSeq]
UniProt Comments for PTPRS
PTPRS: Interacts with LAR-interacting protein LIP.1. Belongs to the protein-tyrosine phosphatase family. Receptor class 2A subfamily. 7 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 3.1.3.48; Membrane protein, integral; Receptor protein phosphatase, tyrosine; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 19p13.3

Cellular Component: integral to plasma membrane

Molecular Function: protein binding; transmembrane receptor protein tyrosine phosphatase activity

Biological Process: corpus callosum development; extracellular matrix organization and biogenesis; spinal cord development; hippocampus development; cerebellum development; cerebral cortex development; cell adhesion
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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