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anti-PRRX2 antibody :: Mouse anti-Human PRRX2 Polyclonal Antibody

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Catalog # MBS6012048
Unit / Price
  0.05 mg  /  $580 +1 FREE 8GB USB
anti-PRRX2 antibody
Product Name

PRRX2, Polyclonal Antibody

Also Known As

PRRX2 (Paired Mesoderm Homeobox Protein 2, Paired-related Homeobox Protein 2, PMX2, PRX2, PRX-2)

Product Synonym Names
Anti -PRRX2 (Paired Mesoderm Homeobox Protein 2, Paired-related Homeobox Protein 2, PMX2, PRX2, PRX-2)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence
MDSAAAAFAL DKPALGPGPP PPPPALGPGD CAQARKNFSV SHLLDLEEVA AAGRLAARPG ARAEAREGAA REPSGGSSGS EAAPQDGECP SPGRGSAAKR KKKQRRNRTT FNSSQLQALE RVFERTHYPD AFVREELARR VNLSEARVQV WFQNRRAKFR RNERAMLASR SASLLKSYSQ EAAIEQPVAP RPTALSPDYL SWTASSPYST VPPYSPGSSG PATPGVNMAN SIASLRLKAK EFSLHHSQVP TVN
Chromosome Location
Chromosome: 9; NC_000009.11 (132427920..132484953). Location: 9q34.1
OMIM
604675
3D Structure
ModBase 3D Structure for Q99811
Clonality
Polyclonal
Isotype
IgG
Host
Mouse
Species Reactivity
Human
Specificity
Recognizes human PRRX2.
Purity/Purification
Affinity Purified
Purified by Protein A affinity chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2.
Immunogen
Full length human PRRX2, aa1-253 (NP_057391.1).
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Other Notes
Small volumes of anti-PRRX2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-PRRX2 antibody
Western Blot (WB)
Application Notes for anti-PRRX2 antibody
Suitable for use in Western Blot.
NCBI/Uniprot data below describe general gene information for PRRX2. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
27,079 Da[Similar Products]
NCBI Official Full Name
paired mesoderm homeobox protein 2
NCBI Official Synonym Full Names
paired related homeobox 2
NCBI Official Symbol
PRRX2  [Similar Products]
NCBI Official Synonym Symbols
PMX2; PRX2
  [Similar Products]
NCBI Protein Information
paired mesoderm homeobox protein 2; PRX-2; paired-related homeobox protein 2; paired-like homeodomain protein PRX2
UniProt Protein Name
Paired mesoderm homeobox protein 2
UniProt Synonym Protein Names
Paired-related homeobox protein 2
UniProt Gene Name
PRRX2  [Similar Products]
UniProt Synonym Gene Names
PMX2; PRX2; PRX-2  [Similar Products]
UniProt Entry Name
PRRX2_HUMAN
NCBI Summary for PRRX2
The DNA-associated protein encoded by this gene is a member of the paired family of homeobox proteins. Expression is localized to proliferating fetal fibroblasts and the developing dermal layer, with downregulated expression in adult skin. Increases in expression of this gene during fetal but not adult wound healing suggest a possible role in mechanisms that control mammalian dermal regeneration and prevent formation of scar response to wounding. The expression patterns provide evidence consistent with a role in fetal skin development and a possible role in cellular proliferation. [provided by RefSeq, Jul 2008]
UniProt Comments for PRRX2
PRRX2: May play a role in the scarless healing of cutaneous wounds during the first two trimesters of development. Belongs to the paired homeobox family.

Protein type: DNA-binding; Transcription factor

Chromosomal Location of Human Ortholog: 9q34.1

Cellular Component: nucleus

Molecular Function: sequence-specific DNA binding; transcription factor activity

Biological Process: inner ear morphogenesis; regulation of transcription, DNA-dependent; cartilage development; positive regulation of mesenchymal cell proliferation; artery morphogenesis; positive regulation of smoothened signaling pathway; embryonic cranial skeleton morphogenesis; middle ear morphogenesis; embryonic limb morphogenesis
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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