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anti-S100A7 antibody :: Goat Psoriasin/S100A7 Polyclonal Antibody

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Catalog # MBS420939
Unit / Price
  0.1 mg  /  $300 +1 FREE 8GB USB
Product Name

Psoriasin/S100A7, Polyclonal Antibody

Popular Item
Also Known As

Goat anti-Psoriasin/S100A7 Antibody

Product Synonym Names
S100A7; S100 calcium binding protein A7 (psoriasin 1); HGNC: 10497; PSOR1; S100A7c; S100 calcium-binding protein A7; S100 calcium-binding protein A7 (psoriasin 1); psoriasin 1; Psoriasin; S100A7 antibody; S100 calcium binding protein A7 (psoriasin 1) antibody; HGNC: 10497 antibody; PSOR1 antibody; S100A7c antibody; S100 calcium-binding protein A7 antibody; S100 calcium-binding protein A7 (psoriasin 1) antibody; psoriasin 1 antibody; Psoriasin antibody; Psoriasin; Psoriasin / S100A7
Antibody/Peptide Pairs
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence Length
101
Immunogen Sequence
HKYTRRDDKI DKP
OMIM
600353
Clonality
Polyclonal
Host
Goat
Species Reactivity
Tested: Human; Expected from sequence similarity: Human
Purity/Purification
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Form/Format
Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Concentration
100ug specific antibody in 200ul (lot specific)
Immunogen
Peptide with sequence C-HKYTRRDDKIDKP, from the internal region of the protein sequence according to NP_002954.1.
Epitope
Internal region
Preparation and Storage
Aliquot and store at -20 degree C. Minimize freezing and thawing.
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Other Notes
Small volumes of anti-S100A7 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-S100A7 antibody
Peptide ELISA (EIA), Western Blot (WB)
Application Notes for anti-S100A7 antibody
Peptide ELISA: Antibody detection limit dilution 1: 32000.

Western Blot (WB) of anti-S100A7 antibody
(0.1ug/ml) staining of Human Skin lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
anti-S100A7 antibody Western Blot (WB) (WB) image
Western Blot (WB) of anti-S100A7 antibody
HEK293 lysate (10ug protein in RIPA buffer) overexpressing Human S100A7 with C-terminal MYC tag probed (0.5ug/ml) in Lane A and probed with anti-MYC Tag (1/1000) in lane C. Mock-transfected HEK293 probed (1mg/ml) in Lane B. Primary incubations were for 1 hour. Detected by chemiluminescence.
anti-S100A7 antibody Western Blot (WB) (WB) image
NCBI/Uniprot data below describe general gene information for S100A7. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
11,471 Da
NCBI Official Full Name
S100 calcium-binding protein A7
NCBI Official Synonym Full Names
S100 calcium binding protein A7
NCBI Official Symbol
S100A7  [Similar Products]
NCBI Official Synonym Symbols
PSOR1; S100A7c
  [Similar Products]
NCBI Protein Information
protein S100-A7
UniProt Protein Name
Protein S100-A7
UniProt Synonym Protein Names
Psoriasin; S100 calcium-binding protein A7
Protein Family
UniProt Gene Name
S100A7  [Similar Products]
UniProt Synonym Gene Names
PSOR1; S100A7C  [Similar Products]
UniProt Entry Name
S10A7_HUMAN
NCBI Summary for S100A7
The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein differs from the other S100 proteins of known structure in its lack of calcium binding ability in one EF-hand at the N-terminus. The protein is overexpressed in hyperproliferative skin diseases, exhibits antimicrobial activities against bacteria and induces immunomodulatory activities. [provided by RefSeq, Nov 2014]
UniProt Comments for S100A7
S100A7: is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein differs from the other S100 proteins of known structure in its lack of calcium binding ability in one EF-hand at the N-terminus. This protein is markedly over-expressed in the skin lesions of psoriatic patients, but is excluded as a candidate gene for familial psoriasis susceptibility. The exact function of this protein is not known. [provided by RefSeq, Jul 2008]

Chromosomal Location of Human Ortholog: 1q21

Cellular Component: cytoplasm; cytosol; endoplasmic reticulum; extracellular region; focal adhesion; nucleus

Molecular Function: calcium ion binding; protein binding; RAGE receptor binding; zinc ion binding

Biological Process: angiogenesis; defense response to Gram-negative bacterium; epidermis development; innate immune response; keratinocyte differentiation; response to lipopolysaccharide; response to reactive oxygen species; sequestering of metal ion
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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