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anti-QKI antibody :: Rabbit anti-Human QKI Polyclonal Antibody

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Catalog # MBS7044097
Unit / Price
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  0.05 mL  /  $120 +1 FREE 8GB USB
  0.1 mL  /  $160 +1 FREE 8GB USB
Product Name

QKI, Polyclonal Antibody

Popular Item
Full Product Name

QKI Antibody

Product Synonym Names
Protein quaking; Hqk; HqkI; QKI; HKQ
Product Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
OMIM
609590
3D Structure
ModBase 3D Structure for Q96PU8
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Purity/Purification
Antigen Affinity Purified
Form/Format
Liquid
Species
Human
Immunogen
Recombinant human Protein quaking protein (1-341AA)
Conjugate
Non-conjugated
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-103851
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of anti-QKI antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-QKI antibody
RNA-binding protein that plays a central role in myelinization (PubMed:16641098). Binds to the 5'-NACUAAY-N(1,20)-UAAY-3' RNA core sequence. Regulates target mRNA stability (PubMed:23630077). In addition, acts by regulating pre-mRNA splicing, mRNA export and protein translation. Required to protect and promote stability of mRNAs such as MBP and CDKN1B. Regulator of oligodendrocyte differentiation and maturation in the brain that may play a role in myelin and oligodendrocyte dysfunction in schizophrenia (PubMed:16641098). Participates in mRNA transport by regulating the nuclear export of MBP mRNA. Also involved in regulation of mRNA splicing of MAG pre-mRNA. Acts as a translational repressor (By similarity).
Applications Tested/Suitable for anti-QKI antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)

Western Blot (WB) of anti-QKI antibody
Western blot
All lanes: QKI antibody at 1.92ug/ml
Lane 1:HL-60 whole cell lysate
Lane 2:Hela whole cell lysate
Lane 3:K562 whole cell lysate
Secondary
Goat polyclonal to rabbit at 1/10000 dilution
Predicted band size: 38,37,36 kDa
Observed band size: 38 kDa,70 kDa

anti-QKI antibody Western Blot (WB) (WB) image
Immunohistochemistry (IHC) of anti-QKI antibody
Immunohistochemistry of paraffin-embedded human testis using MBS7044097 at dilution 1:100
anti-QKI antibody Immunohistochemistry (IHC) (IHC) image
Immunohistochemistry (IHC) of anti-QKI antibody
Immunohistochemistry of paraffin-embedded human brain tissue using MBS7044097 at dilution 1:100
anti-QKI antibody Immunohistochemistry (IHC) (IHC) image
NCBI/Uniprot data below describe general gene information for QKI. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
35,131 Da
NCBI Official Full Name
protein quaking isoform 5
NCBI Official Synonym Full Names
QKI, KH domain containing RNA binding
NCBI Official Symbol
NCBI Official Synonym Symbols
QK; Hqk; QK1; QK3; hqkI
  [Similar Products]
NCBI Protein Information
protein quaking
UniProt Protein Name
Protein quaking
Protein Family
UniProt Gene Name
UniProt Synonym Gene Names
HKQ; Hqk; HqkI  [Similar Products]
UniProt Entry Name
QKI_HUMAN
NCBI Summary for QKI
The protein encoded by this gene is an RNA-binding protein that regulates pre-mRNA splicing, export of mRNAs from the nucleus, protein translation, and mRNA stability. The encoded protein is involved in myelinization and oligodendrocyte differentiation and may play a role in schizophrenia. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014]
UniProt Comments for QKI
RNA-binding protein that plays a central role in myelinization (PubMed:16641098). Binds to the 5'-NACUAAY-N(1,20)-UAAY-3' RNA core sequence. Regulates target mRNA stability (PubMed:23630077). In addition, acts by regulating pre-mRNA splicing, mRNA export and protein translation. Required to protect and promote stability of mRNAs such as MBP and CDKN1B. Regulator of oligodendrocyte differentiation and maturation in the brain that may play a role in myelin and oligodendrocyte dysfunction in schizophrenia (PubMed:16641098). Participates in mRNA transport by regulating the nuclear export of MBP mRNA. Also involved in regulation of mRNA splicing of MAG pre-mRNA. Acts as a translational repressor ().
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Pathways associated with anti-QKI antibody
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