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anti-RAB11FIP1 antibody :: Goat RAB11FIP1/RCP Polyclonal Antibody

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Catalog # MBS420243
Unit / Price
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  0.1 mg  /  $300 +1 FREE 8GB USB
Western Blot (WB)
Product Name

RAB11FIP1/RCP, Polyclonal Antibody

Full Product Name

Goat anti-RAB11FIP1/RCP Antibody

Product Synonym Names
RAB11FIP1; RAB11 family interacting protein 1 (class I); HGNC: 30265; FLJ22524; FLJ22622; MGC78448; NOEL1A; RCP; rab11-FIP1; Rab coupling protein; Rab effector protein; Rab-interacting recycling protein; Rab11-family interacting protein 1D; no Rab11-bindi; RAB11FIP1 antibody; RAB11 family interacting protein 1 (class I) antibody; HGNC: 30265 antibody; FLJ22524 antibody; FLJ22622 antibody; MGC78448 antibody; NOEL1A antibody; RCP antibody; rab11-FIP1 antibody; Rab coupling protein antibody; Rab effector protein antibody; Rab-interacting recycling protein antibody; Rab11-family interacting protein 1D antibody; no Rab11-binding protein 1A antibody; DKFZp686E2214 antibody; RAB11 coupling protein antibody; RAB11 family interacting protein 1 antibody; RAB11FIP1 / RCP
Product Synonym Gene Name
Antibody/Peptide Pairs
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence
EATKEAKESK KPE
OMIM
608737
Clonality
Polyclonal
Host
Goat
Species Reactivity
Tested: Human; Expected from sequence similarity: Human
Purity/Purification
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Form/Format
Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Concentration
100ug specific antibody in 200ul (lot specific)
Immunogen
Peptide with sequence C-EATKEAKESKKPE, from the internal region of the protein sequence according to NP_079427.3; NP_001002814.1.
Epitope
Internal region
Note
This antibody is expected to recognise isoform 1 (NP_079427.3) and isoform 3 (NP_001002814.1).
Preparation and Storage
Aliquot and store at -20 degree C. Minimize freezing and thawing.
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of anti-RAB11FIP1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-RAB11FIP1 antibody
Peptide ELISA (EIA), Western Blot (WB)
Application Notes for anti-RAB11FIP1 antibody
Peptide ELISA: Antibody detection limit dilution 1: 64000.
Western Blot: Approx 80kDa band observed in lysates of cell line HeLa (calculated MW of 71. 0kDa according to NP_079427.3). The observed molecular weight of 80kDa corresponds to earlier findings in literature with different antibodies (Lindsay et al, J Biol Chem.2002 Apr 5;277(14): 12190-9. PMID 11786538. ). Recommended concentration: 0.1-0.3ug/ml.

Western Blot (WB) of anti-RAB11FIP1 antibody
(0.2ug/ml) staining of HeLa lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
anti-RAB11FIP1 antibody Western Blot (WB) (WB) image
NCBI/Uniprot data below describe general gene information for RAB11FIP1. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI Related Accession #
Manufactured in an ISO 9001:2008 Certified Laboratory.NP_001002814.1[Other Products]
NCBI GenBank Nucleotide #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
15,304 Da
NCBI Official Full Name
RAB11 family interacting protein 1 isoform 1
NCBI Official Synonym Full Names
RAB11 family interacting protein 1
NCBI Official Symbol
RAB11FIP1  [Similar Products]
NCBI Official Synonym Symbols
RCP; NOEL1A; rab11-FIP1
  [Similar Products]
NCBI Protein Information
rab11 family-interacting protein 1
UniProt Protein Name
Rab11 family-interacting protein 1
UniProt Synonym Protein Names
Rab-coupling protein
UniProt Gene Name
RAB11FIP1  [Similar Products]
UniProt Synonym Gene Names
RCP; Rab11-FIP1  [Similar Products]
UniProt Entry Name
RFIP1_HUMAN
NCBI Summary for RAB11FIP1
This gene encodes one of the Rab11-family interacting proteins (Rab11-FIPs), which play a role in the Rab-11 mediated recycling of vesicles. The encoded protein may be involved in endocytic sorting, trafficking of proteins including integrin subunits and epidermal growth factor receptor (EGFR), and transport between the recycling endosome and the trans-Golgi network. Alternative splicing results in multiple transcript variants. A pseudogene is described on the X chromosome. [provided by RefSeq, Dec 2013]
UniProt Comments for RAB11FIP1
RAB11FIP1: A Rab11 effector protein involved in the endosomal recycling process. Also involved in controlling membrane trafficking along the phagocytic pathway and in phagocytosis. Homooligomer (isoform 2). Isoform 2 interacts with RAB4A, RAB11A, RAB11B and RAB25. According to PubMed:15280022, RAB4A binding to RAB11FIP1 is of very low affinity in vitro and in vivo. Isoform 2 is expressed in brain, heart, testis, lung, spleen, ovary and small intestine. 5 isoforms of the human protein are produced by alternative splicing.

Protein type: Vesicle

Chromosomal Location of Human Ortholog: 8p11.22

Cellular Component: cytoplasm; intracellular membrane-bound organelle; phagocytic vesicle membrane; recycling endosome

Molecular Function: Rab GTPase binding

Biological Process: protein transport; regulated secretory pathway
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Products associated with anti-RAB11FIP1 antibody
Pathways associated with anti-RAB11FIP1 antibody
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