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anti-RBM22 antibody :: Rabbit anti-Human RBM22 Polyclonal Antibody

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Catalog # MBS7000347
Unit / Price
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  0.05 mg  /  $160 +1 FREE 8GB USB
  0.1 mg  /  $235 +1 FREE 8GB USB
Product Name

RBM22, Polyclonal Antibody

Popular Item
Full Product Name

RBM22 Antibody

Product Synonym Names
Pre-mRNA-splicing factor RBM22; RNA-binding motif protein 22; Zinc finger CCCH domain-containing protein 16; RBM22; ZC3H16; 199G4
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
OMIM
612430
3D Structure
ModBase 3D Structure for Q9NW64
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Purity/Purification
>95%,Protein G purified
Form/Format
Liquid
Immunogen
Recombinant human Pre-mRNA-splicing factor RBM22 protein
Conjugation
Non-conjugated
Storage Buffer
Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-132056 / sc-132057 / sc-132058 / sc-102074
Preparation and Storage
Shipped at 4 degree C. Upon delivery, aliquot and store at -20 degree C or -80 degree C.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of anti-RBM22 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-RBM22 antibody
Involved in the first step of pre-mRNA splicing. Binds directly to the internal stem-loop (ISL) domain of the U6 snRNA and to the pre-mRNA intron near the 5' splice site during the activation and catalytic phases of the spliceosome cycle. Involved in both translocations of the nuclear SLU7 to the cytoplasm and the cytosolic calcium-binding protein PDCD6 to the nucleus upon cellular stress responses.
Applications Tested/Suitable for anti-RBM22 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)

Western Blot (WB) of anti-RBM22 antibody
Western Blot
Positive WB detected in:Raji whole cell lysate,NIH/3T3 whole cell lysate,HL-60 whole cell lysate,Mouse skeletal muscle tissue
All lanes: RBM22 antibody at 2.7ug/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 47,42 kDa
Observed band size: 47 kDa

anti-RBM22 antibody Western Blot (WB) (WB) image
Immunohistochemistry (IHC) of anti-RBM22 antibody
Immunohistochemistry of paraffin-embedded human glioma cancer using MBS7000347 at dilution of 1:100
anti-RBM22 antibody Immunohistochemistry (IHC) (IHC) image
NCBI/Uniprot data below describe general gene information for RBM22. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
41,152 Da
NCBI Official Full Name
pre-mRNA-splicing factor RBM22
NCBI Official Synonym Full Names
RNA binding motif protein 22
NCBI Official Symbol
RBM22  [Similar Products]
NCBI Official Synonym Symbols
Cwc2; ZC3H16; fSAP47
  [Similar Products]
NCBI Protein Information
pre-mRNA-splicing factor RBM22
UniProt Protein Name
Pre-mRNA-splicing factor RBM22
UniProt Synonym Protein Names
RNA-binding motif protein 22; Zinc finger CCCH domain-containing protein 16
Protein Family
UniProt Gene Name
RBM22  [Similar Products]
UniProt Synonym Gene Names
ZC3H16  [Similar Products]
UniProt Entry Name
RBM22_HUMAN
NCBI Summary for RBM22
This gene encodes an RNA binding protein. The encoded protein may play a role in cell division and may be involved in pre-mRNA splicing. Related pseudogenes exist on chromosomes 6, 7, 9, 13, 16, 18, and X. [provided by RefSeq, Mar 2009]
UniProt Comments for RBM22
RBM22: Involved in the first step of pre-mRNA splicing. Binds directly to the internal stem-loop (ISL) domain of the U6 snRNA and to the pre-mRNA intron near the 5' splice site during the activation and catalytic phases of the spliceosome cycle. Involved in both translocations of the nuclear SLU7 to the cytoplasm and the cytosolic calcium-binding protein PDCD6 to the nucleus upon cellular stress responses. Belongs to the SLT11 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: RNA-binding; RNA processing; RNA splicing; Spliceosome

Chromosomal Location of Human Ortholog: 5q33.1

Cellular Component: cytoplasm; nucleoplasm; nucleus

Molecular Function: calcium-dependent protein binding; metal ion binding; nucleocytoplasmic transporter activity; nucleotide binding; protein binding; U6 snRNA binding

Biological Process: nuclear mRNA cis splicing, via U2-type spliceosome; nuclear mRNA splicing, via spliceosome; positive regulation of RNA splicing; protein import into nucleus, translocation; spliceosomal snRNP biogenesis
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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