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anti-RCL antibody :: Rabbit anti-Human RCL Polyclonal Antibody

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Catalog # MBS9605407
Unit / Price
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  0.1 mL  /  $255 +1 FREE 8GB USB
  0.2 mL  /  $295 +1 FREE 8GB USB
Product Name

RCL, Polyclonal Antibody

Popular Item
Full Product Name

RCL Antibody

Product Synonym Names
2' deoxynucleoside 5' phosphate N hydrolase 1; BC048355; c Myc responsive; c Myc responsive protein Rcl; c-Myc-responsive protein Rcl; C6orf108; C76683; Chromosome 6 open reading frame 108; Deoxyribonucleoside 5' monophosphate N glycosidase; Deoxyribonucleoside 5''-monophosphate N-glycosidase; dJ330M21.3; DNPH1; MGC54855; Putative c Myc responsive; Rcl; RCL_HUMAN; RP3 330M21.3
Product Gene Name
Product Synonym Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for O43598
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Specificity
RCL antibody detects endogenous levels of total RCL
Purity/Purification
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
Form/Format
Liquid
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1mg/ml (lot specific)
Immunogen
A synthesized peptide
Subcellular Location
Nucleus. Cytoplasm.
Tissue Specificity
Expressed at low levels in brain, colon, lung, peripheral blood leukocytes, placenta, small intestine, and thymus. Expressed at high levels in heart, kidney, liver, skeletal muscle and spleen. Overexpressed in a significant proportion of breast cancers.
Predicted Cross Reactivity
Pig, Bovine, Sheep, Rabbit, Dog, Xenopus
Similarity
Pig (80%), Bovine (90%), Sheep (90%), Rabbit (80%), Dog (90%), Xenopus (82%)
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C. Stable for 12 months from date of receipt.
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Supply Chain Verification
Manufactured in a lab with traceable raw materials manufactured on site. Coordinated product portfolio of antibodies, pairs, conjugates, recombinant proteins, and immunoassay materials available, please inquire.
Other Notes
Small volumes of anti-RCL antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-RCL antibody
Function: Catalyzes the cleavage of the N-glycosidic bond of deoxyribonucleoside 5'-monophosphates to yield deoxyribose 5-phosphate and a purine or pyrimidine base. Deoxyribonucleoside 5'-monophosphates containing purine bases are preferred to those containing pyrimidine bases.
Subunit Structure: Monomer and homodimer.
Similarity: Belongs to the 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 family.
Applications Tested/Suitable for anti-RCL antibody
Western Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA)
Application Notes for anti-RCL antibody
WB: 1:500-1:1000
IF/ICC: 1:100-1:500

Western Blot (WB) of anti-RCL antibody
Western blot analysis of extracts from K562 cells using RCL antibody.
anti-RCL antibody Western Blot (WB) (WB) image
Immunofluorescene (IF) of anti-RCL antibody
MBS9605407 staining Hela cells by IF/ICC. The sample were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 minutes at 25 degree C. The primary antibody was diluted at 1/200 and incubated with the sample for 1 hour at 37 degree C. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) antibody, diluted at 1/600, was used as secondary antibody.
anti-RCL antibody Immunofluorescene (IF) image
NCBI/Uniprot data below describe general gene information for RCL. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
Observed: 22 kD
Predicted: 20 kDa
NCBI Official Full Name
2'-deoxynucleoside 5'-phosphate N-hydrolase 1 isoform 1
NCBI Official Synonym Full Names
2'-deoxynucleoside 5'-phosphate N-hydrolase 1
NCBI Official Symbol
DNPH1  [Similar Products]
NCBI Official Synonym Symbols
RCL; C6orf108; dJ330M21.3
  [Similar Products]
NCBI Protein Information
2'-deoxynucleoside 5'-phosphate N-hydrolase 1
UniProt Protein Name
2'-deoxynucleoside 5'-phosphate N-hydrolase 1
UniProt Synonym Protein Names
c-Myc-responsive protein RCLUniRule annotationManual assertion according to rulesiHAMAP-Rule:MF_03036
UniProt Gene Name
DNPH1  [Similar Products]
UniProt Synonym Gene Names
C6orf108; RCLUniRule annotationManual assertion according to rulesiHAMAP-Rule:MF_03036  [Similar Products]
NCBI Summary for RCL
This gene was identified on the basis of its stimulation by c-Myc protein. The latter is a transcription factor that participates in the regulation of cell proliferation, differentiation, and apoptosis. The exact function of this gene is not known but studies in rat suggest a role in cellular proliferation and c-Myc-mediated transformation. Two alternative transcripts encoding different proteins have been described. [provided by RefSeq, Jul 2008]
UniProt Comments for RCL
Catalyzes the cleavage of the N-glycosidic bond of deoxyribonucleoside 5'-monophosphates to yield deoxyribose 5-phosphate and a purine or pyrimidine base. Deoxyribonucleoside 5'-monophosphates containing purine bases are preferred to those containing pyrimidine bases.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Diseases associated with anti-RCL antibody
 Disease Name  Pubmed Publications
 Fatty Liver Antibodies  >1 publications with RCL and Fatty Liver
Organs/Tissues associated with anti-RCL antibody
 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >2 publications with RCL and Liver
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