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anti-S100A14 antibody :: Rabbit anti-Human S100A14 Polyclonal Antibody

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Catalog # MBS7046551
Unit / Price
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  0.05 mL  /  $120 +1 FREE 8GB USB
  0.1 mL  /  $160 +1 FREE 8GB USB
Product Name

S100A14, Polyclonal Antibody

Popular Item
Full Product Name

S100A14 Antibody

Product Synonym Names
Protein S100-A14; S100 calcium-binding protein A14; S114; S100A14; S100A15
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
OMIM
607986
3D Structure
ModBase 3D Structure for Q9HCY8
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Purity/Purification
Antigen Affinity Purified
Form/Format
Liquid
Species
Human
Immunogen
Recombinant human Protein S100-A14 protein (1-104AA)
Conjugate
Non-conjugated
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of anti-S100A14 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-S100A14 antibody
Modulates P53/TP53 protein levels, and thereby plays a role in the regulation of cell survival and apoptosis. Depending on the context, it can promote cell proliferation or apoptosis. Plays a role in the regulation of cell migration by modulating the levels of MMP2, a matrix protease that is under transcriptional control of P53/TP53. Does not bind calcium.
Applications Tested/Suitable for anti-S100A14 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)

Western Blot (WB) of anti-S100A14 antibody
Western blot
All lanes: S100A14 antibody at 4.11 ug/ml+ A431 whole cell lysate
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 12 kDa
Observed band size: 12 kDa

anti-S100A14 antibody Western Blot (WB) (WB) image
Immunohistochemistry (IHC) of anti-S100A14 antibody
Immunohistochemistry of paraffin-embedded human colon cancer using MBS7046551 at dilution of 1:100
anti-S100A14 antibody Immunohistochemistry (IHC) (IHC) image
Immunohistochemistry (IHC) of anti-S100A14 antibody
Immunohistochemistry of paraffin-embedded human skin tissue using MBS7046551 at dilution of 1:100
anti-S100A14 antibody Immunohistochemistry (IHC) (IHC) image
NCBI/Uniprot data below describe general gene information for S100A14. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
11,662 Da
NCBI Official Full Name
protein S100-A14
NCBI Official Synonym Full Names
S100 calcium binding protein A14
NCBI Official Symbol
S100A14  [Similar Products]
NCBI Official Synonym Symbols
BCMP84; S100A15
  [Similar Products]
NCBI Protein Information
protein S100-A14
UniProt Protein Name
Protein S100-A14
UniProt Synonym Protein Names
S100 calcium-binding protein A14; S114
Protein Family
UniProt Gene Name
S100A14  [Similar Products]
UniProt Synonym Gene Names
S100A15; S114  [Similar Products]
UniProt Entry Name
S10AE_HUMAN
NCBI Summary for S100A14
This gene encodes a member of the S100 protein family which contains an EF-hand motif and binds calcium. The gene is located in a cluster of S100 genes on chromosome 1. Levels of the encoded protein have been found to be lower in cancerous tissue and associated with metastasis suggesting a tumor suppressor function (PMID: 19956863, 19351828). [provided by RefSeq, Dec 2011]
UniProt Comments for S100A14
S100A14: a member of the S100 protein family which contains an EF-hand motif and binds calcium. The gene is located in a cluster of S100 genes on chromosome 1. Levels of the encoded protein have been found to be lower in cancerous tissue and associated with metastasis suggesting a tumor suppressor function (PMID: 19956863, 19351828). [provided by RefSeq, Dec 2011]

Protein type: Unknown function

Chromosomal Location of Human Ortholog: 1q21.3

Cellular Component: cell junction; cytoplasm; microtubule cytoskeleton; nucleoplasm; perinuclear region of cytoplasm; plasma membrane

Molecular Function: chemokine receptor binding; protein binding

Biological Process: defense response to bacterium; response to lipopolysaccharide; toll-like receptor 4 signaling pathway
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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