View our list of available Coronavirus (COVID-19, SARS-CoV-2, 2019-nCOV) antibodies, recombinant proteins, ELISA Kits... Options Full Datasheet Printer Friendly Datasheet Prepare for Printing Full Datasheet Printer Friendly Datasheet Prepare for Printing Have Questions? Ask Us! Request A Quote Today! Add To Compare List anti-SAMHD1 antibody :: Rabbit SAMHD1 Polyclonal Antibody Catalog # MBS9128663 (SPECIAL PROMOTION: Get FREE $5 Amazon gift card (Maximum 5 gift cards/product). Gift card(s) will be included with shipment) Unit / Price 0.02 mL / $230 +1 FREE 8GB USB 0.05 mL / $305 +1 FREE 8GB USB 0.1 mL / $440 +1 FREE 8GB USB 0.2 mL / $610 +1 FREE 8GB USB 5x0.2 mL / $2,535 +3 FREE 8GB USB Previous Next Product Name Product Info Accession #s Product Desc Diseases/Tissues/Pathways Applications References Product Name SAMHD1, Polyclonal Antibody Popular Item Full Product Name SAMHD1 Polyclonal Antibody Product Gene Name anti-SAMHD1 antibody[Similar Products] Research Use Only For Research Use Only. Not for use in diagnostic procedures. TOP OMIM 606754 3D Structure ModBase 3D Structure for Q9Y3Z3 Clonality Polyclonal Isotype IgG Host Rabbit Species Reactivity Human, Mouse, Rat Purity/Purification Affinity Purification Immunogen Recombinant Protein Immunogen Recombinant protein of human SAMHD1 Preparation and Storage Store at -20 degree C. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. ISO Certification Manufactured in an ISO 9001:2015 Certified Laboratory. Other Notes Small volumes of anti-SAMHD1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply. TOP Related Product Information for anti-SAMHD1 antibody This gene may play a role in regulation of the innate immune response. The encoded protein is upregulated in response to viral infection and may be involved in mediation of tumor necrosis factor-alpha proinflammatory responses. Mutations in this gene have been associated with Aicardi-Goutieres syndrome. Applications Tested/Suitable for anti-SAMHD1 antibody Western Blot (WB), Immunohistochemistry (IHC), Immunofluoresence (IF) Application Notes for anti-SAMHD1 antibody WB 1:500 - 1:2000IHC 1:50 - 1:200IF 1:50 - 1:100 Western Blot (WB) of anti-SAMHD1 antibody Western blot analysis of extracts of various cell lines, using SAMHD1 antibody at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (MBS128200) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit.Exposure time: 90s. Immunofluorescence (IF) of anti-SAMHD1 antibody Immunofluorescence analysis of A549 cells using SAMHD1 antibody. Blue: DAPI for nuclear staining. TOP NCBI/Uniprot data below describe general gene information for SAMHD1. It may not necessarily be applicable to this product. NCBI GI # 38016914 NCBI GeneID 25939 NCBI Accession # NP_056289.2 [Other Products] NCBI GenBank Nucleotide # NM_015474.3 [Other Products] UniProt Primary Accession # Q9Y3Z3 [Other Products] UniProt Secondary Accession # Q5JXG8; Q8N491; Q9H004; Q9H005; Q9H3U9; B4E2A5; E1P5V2[Other Products] UniProt Related Accession # Q9Y3Z3[Other Products] Molecular Weight 72kDa TOP NCBI Official Full Name deoxynucleoside triphosphate triphosphohydrolase SAMHD1 NCBI Official Synonym Full Names SAM domain and HD domain 1 NCBI Official Symbol SAMHD1 [Similar Products] NCBI Official Synonym Symbols DCIP; CHBL2; HDDC1; MOP-5; SBBI88 [Similar Products] NCBI Protein Information deoxynucleoside triphosphate triphosphohydrolase SAMHD1 UniProt Protein Name Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 UniProt Synonym Protein Names Dendritic cell-derived IFNG-induced protein; DCIP; Monocyte protein 5; MOP-5; SAM domain and HD domain-containing protein 1 Protein Family Deoxynucleoside triphosphate triphosphohydrolase UniProt Gene Name SAMHD1 [Similar Products] UniProt Synonym Gene Names MOP5; dNTPase; DCIP; MOP-5 [Similar Products] UniProt Entry Name SAMH1_HUMAN TOP NCBI Summary for SAMHD1 This gene may play a role in regulation of the innate immune response. The encoded protein is upregulated in response to viral infection and may be involved in mediation of tumor necrosis factor-alpha proinflammatory responses. Mutations in this gene have been associated with Aicardi-Goutieres syndrome. [provided by RefSeq, Mar 2010] TOP UniProt Comments for SAMHD1 SAMHD1: a protein induced by interferon gamma.Protein type: EC 3.1.4.-Chromosomal Location of Human Ortholog: 20pter-q12Cellular Component: nucleoplasm; plasma membrane; intracellular; nucleusMolecular Function: protein binding; nucleic acid binding; dGTPase activity; zinc ion binding; RNA binding; dGTP bindingBiological Process: dGTP catabolic process; dATP catabolic process; cytokine and chemokine mediated signaling pathway; immune response; defense response to virus; protein homotetramerization; regulation of innate immune responseDisease: Chilblain Lupus 2; Aicardi-goutieres Syndrome 5 Research Articles on SAMHD1 1. Data indicate that proline residue P109 within the C-terminal poly-proline motif (PPM) of Vpx protein plays a unique role in the regulation of SAM domain and HD domain 1 protein SAMHD1 degradation. TOP Precautions All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines. Disclaimer While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information. TOP Products associated with anti-SAMHD1 antibody Reference Product PubMed Publications CDK1 antibody >7 publications with SAMHD1 and CDK1 DDB1 antibody >6 publications with SAMHD1 and DDB1 RNASEH2A antibody >6 publications with SAMHD1 and RNASEH2A VPRBP antibody >6 publications with SAMHD1 and VPRBP RNASEH2C antibody >5 publications with SAMHD1 and RNASEH2C RNASEH2B antibody >5 publications with SAMHD1 and RNASEH2B KPNB1 antibody >2 publications with SAMHD1 and KPNB1 TK2 antibody >1 publications with SAMHD1 and TK2 UBC antibody >1 publications with SAMHD1 and UBC Pathways associated with anti-SAMHD1 antibody Products by Pathway Pathway Diagram Cytokine Signaling In Immune System Pathway antibodies Cytokine Signaling In Immune System Pathway Diagram Immune System Pathway antibodies Immune System Pathway Diagram Interferon Signaling Pathway antibodies Interferon Signaling Pathway Diagram Interferon Alpha/beta Signaling Pathway antibodies Interferon Alpha/beta Signaling Pathway Diagram Diseases associated with anti-SAMHD1 antibody Disease Name Pubmed Publications Aicardi-Goutieres syndrome Antibodies >60 publications with SAMHD1 and Aicardi-Goutieres syndrome Nervous System Diseases Antibodies >43 publications with SAMHD1 and Nervous System Diseases Inflammation Antibodies >7 publications with SAMHD1 and Inflammation Aicardi-Goutieres syndrome 5 Antibodies >6 publications with SAMHD1 and Aicardi-Goutieres syndrome 5 Necrosis Antibodies >5 publications with SAMHD1 and Necrosis Hemorrhage Antibodies >4 publications with SAMHD1 and Hemorrhage Thrombocytopenia Antibodies >2 publications with SAMHD1 and Thrombocytopenia Liver Diseases Antibodies >2 publications with SAMHD1 and Liver Diseases Adenocarcinoma Antibodies >2 publications with SAMHD1 and Adenocarcinoma Lung Neoplasms Antibodies >1 publications with SAMHD1 and Lung Neoplasms Organs/Tissues associated with anti-SAMHD1 antibody Organ/Tissue Name Pubmed Publications Blood Antibodies >60 publications with SAMHD1 and Blood Brain Antibodies >10 publications with SAMHD1 and Brain Vascular Antibodies >9 publications with SAMHD1 and Vascular Skin Antibodies >7 publications with SAMHD1 and Skin Lung Antibodies >6 publications with SAMHD1 and Lung Ganglia Antibodies >4 publications with SAMHD1 and Ganglia Lymph Node Antibodies >4 publications with SAMHD1 and Lymph Node Eye Antibodies >4 publications with SAMHD1 and Eye Liver Antibodies >4 publications with SAMHD1 and Liver Spleen Antibodies >3 publications with SAMHD1 and Spleen TOP © 2006-24 MyBioSource.com. 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