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anti-SAA4 antibody :: Goat anti-Human Serum Amyloid A4, Constitutive Polyclonal Antibody

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Catalog # MBS617036
Unit / Price
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  0.1 mg  /  $765 +1 FREE 8GB USB
anti-SAA4 antibody
Product Name

Serum Amyloid A4, Constitutive (SAA4), Polyclonal Antibody

Full Product Name

Serum Amyloid A4, Constitutive (SAA4, CSAA)

Product Synonym Names
Anti -Serum Amyloid A4, Constitutive (SAA4, CSAA)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Chromosome Location
Chromosome: 11; NC_000011.9 (18252902..18258355, complement). Location: 11p15.1-p14
OMIM
104752
3D Structure
ModBase 3D Structure for P35542
Clonality
Polyclonal
Isotype
IgG
Host
Goat
Species Reactivity
Human
Specificity
Recognizes human SAA4. Species Crossreactivity: recombinant mouse SAA4 (~20%). Shows < 5% crossreactivity with recombinant human SAA1.
Purity/Purification
Affinity Purified
Purified by affinity chromatography.
Form/Format
Supplied as a lyophilized powder from PBS, 5% trehalose. Reconstitute with 500ul sterile PBS.
Immunogen
Recombinant corresponding to aa19-130 of human SAA4 (P35542) expressed in E. coli.
Preparation and Storage
Lyophilized powder may be stored at -20 degree C. Stable for 12 months at -20 degree C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Reconstituted product is stable for 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. 
Other Notes
Small volumes of anti-SAA4 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-SAA4 antibody
Serum amyloid A4 (SAA4) is a constitutively expressed SAA protein that is also known as C-SAA. It is an apolipoprotein that constitutes more than 90% of SAA on HDL during homeostasis and may be involved in lipid transfer between lipoprotein classes. Mature human SAA4 contains 112 amino acid (aa) residues. It is primarily produced in hepatocytes and secreted plasma. In solution, SAA4 is reported to form stable dimers and trimers. Human and mouse SAA4 share 57% aa sequence identity.
Product Categories/Family for anti-SAA4 antibody
Applications Tested/Suitable for anti-SAA4 antibody
ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-SAA4 antibody
Suitable for use in Direct ELISA, Western Blot and Immunohistochemistry.
Dilution: Direct ELISA: 0.5-1.0ug/ml; The detection limit for recombinant human SAA4 is ~0.1ng/well.
Western Blot: 0.1-0.2ug/ml; The detection limit for recombinant human SAA4 is ~0.5ng/lane under non-reducing and reducing conditions.
Immunohistochemistry: 2-15ug/ml will detect SAA4 in cells and tissues.
NCBI/Uniprot data below describe general gene information for SAA4. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
14,747 Da[Similar Products]
NCBI Official Full Name
serum amyloid A-4 protein
NCBI Official Synonym Full Names
serum amyloid A4, constitutive
NCBI Official Symbol
NCBI Official Synonym Symbols
CSAA; C-SAA
  [Similar Products]
NCBI Protein Information
serum amyloid A-4 protein; OTTHUMP00000233012; constitutively expressed serum amyloid A protein
UniProt Protein Name
Serum amyloid A-4 protein
UniProt Synonym Protein Names
Constitutively expressed serum amyloid A protein
Protein Family
UniProt Gene Name
UniProt Synonym Gene Names
UniProt Entry Name
SAA4_HUMAN
UniProt Comments for SAA4
SAA4: Major acute phase reactant. Apolipoprotein of the HDL complex. Belongs to the SAA family.

Protein type: Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 11p15.1-p14

Cellular Component: extracellular region

Biological Process: acute-phase response
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Pathways associated with anti-SAA4 antibody
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