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anti-SLC10A2 antibody :: Rabbit anti-Human SLC10A2 Polyclonal Antibody

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Catalog # MBS7005222
Unit / Price
Scan QR to view Datasheet
  0.05 mg  /  $160 +1 FREE 8GB USB
  0.1 mg  /  $235 +1 FREE 8GB USB
Product Name

SLC10A2, Polyclonal Antibody

Popular Item
Full Product Name

SLC10A2 Antibody

Product Synonym Names
Ileal sodium/bile acid cotransporter; Apical sodium-dependent bile acid transporter; ASBT; Ileal Na(+)/bile acid cotransporter; Ileal sodium-dependent bile acid transporter; IBAT; ISBT; Na(+)-dependent ileal bile acid transporter; Sodium/taurocholate cotransporting polypeptide; ileal; Solute carrier family 10 member 2; SLC10A2; ASBT; ISBT; NTCP2
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
OMIM
601295
3D Structure
ModBase 3D Structure for Q12908
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Purity/Purification
>95%,Protein G purified
Form/Format
Liquid
Immunogen
Recombinant human Ileal sodium/bile acid cotransporter protein
Conjugation
Non-conjugated
Storage Buffer
Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-27493
Preparation and Storage
Shipped at 4 degree C. Upon delivery, aliquot and store at -20 degree C or -80 degree C.
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of anti-SLC10A2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-SLC10A2 antibody
Plays a critical role in the sodium-dependent reabsorption of bile acids from the lumen of the small intestine. Plays a key role in cholesterol metabolism.
Applications Tested/Suitable for anti-SLC10A2 antibody
ELISA (EIA), Immunohistochemistry (IHC), Immunofluorescence (IF)

Immunohistochemistry (IHC) of anti-SLC10A2 antibody
Immunohistochemistry of paraffin-embedded human endometrial carcinoma MBS7005222 at dilution 1:100
anti-SLC10A2 antibody Immunohistochemistry (IHC) (IHC) image
Immunofluorescence (IF) of anti-SLC10A2 antibody
Immunofluorescent analysis of A431 cells using MBS7005222 at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
anti-SLC10A2 antibody Immunofluorescence (IF) image
NCBI/Uniprot data below describe general gene information for SLC10A2. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
37,714 Da
NCBI Official Full Name
ileal sodium/bile acid cotransporter
NCBI Official Synonym Full Names
solute carrier family 10 (sodium/bile acid cotransporter), member 2
NCBI Official Symbol
SLC10A2  [Similar Products]
NCBI Official Synonym Symbols
ASBT; IBAT; ISBT; PBAM; NTCP2
  [Similar Products]
NCBI Protein Information
ileal sodium/bile acid cotransporter
UniProt Protein Name
Ileal sodium/bile acid cotransporter
UniProt Synonym Protein Names
Apical sodium-dependent bile acid transporter; ASBT; Ileal Na(+)/bile acid cotransporter; Ileal sodium-dependent bile acid transporter; IBAT; ISBT; Na(+)-dependent ileal bile acid transporter; Sodium/taurocholate cotransporting polypeptide, ileal; Solute carrier family 10 member 2
UniProt Gene Name
SLC10A2  [Similar Products]
UniProt Synonym Gene Names
ASBT; ISBT; NTCP2; ASBT; IBAT; ISBT  [Similar Products]
UniProt Entry Name
NTCP2_HUMAN
NCBI Summary for SLC10A2
This gene encodes a sodium/bile acid cotransporter. This transporter is the primary mechanism for uptake of intestinal bile acids by apical cells in the distal ileum. Bile acids are the catabolic product of cholesterol metabolism, so this protein is also critical for cholesterol homeostasis. Mutations in this gene cause primary bile acid malabsorption (PBAM); muatations in this gene may also be associated with other diseases of the liver and intestines, such as familial hypertriglyceridemia (FHTG). [provided by RefSeq, Mar 2010]
UniProt Comments for SLC10A2
ASBT: Plays a critical role in the sodium-dependent reabsorption of bile acids from the lumen of the small intestine. Plays a key role in cholesterol metabolism. Defects in SLC10A2 are a cause of primary bile acid malabsorption (PBAM). PBAM is an idiopathic intestinal disorder associated with congenital diarrhea, steatorrhea, interruption of the enterohepatic circulation of bile acids, and reduced plasma cholesterol levels. Belongs to the bile acid:sodium symporter (BASS) (TC 2.A.28) family.

Protein type: Membrane protein, integral; Membrane protein, multi-pass; Transporter

Chromosomal Location of Human Ortholog: 13q33

Cellular Component: apical plasma membrane; integral to plasma membrane; microvillus; plasma membrane

Molecular Function: bile acid:sodium symporter activity

Biological Process: bile acid and bile salt transport; bile acid metabolic process; sodium ion transport; transmembrane transport; transport

Disease: Bile Acid Malabsorption, Primary
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Organs/Tissues associated with anti-SLC10A2 antibody
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