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anti-SNAP29 antibody :: Rabbit anti-Human SNAP29 Polyclonal Antibody

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Catalog # MBS7046564
Unit / Price
  0.05 mL  /  $120 +1 FREE 8GB USB
  0.1 mL  /  $160 +1 FREE 8GB USB
Product Name

SNAP29, Polyclonal Antibody

Popular Item
Full Product Name

SNAP29 Antibody

Product Synonym Names
Synaptosomal-associated protein 29Imported; Soluble 29 kDa NSF attachment protein; SNAP29
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
OMIM
604202
3D Structure
ModBase 3D Structure for O95721
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Purity/Purification
Antigen Affinity Purified
Form/Format
Liquid
Species
Human
Immunogen
Recombinant human Synaptosomal-associated protein 29 protein (1-258AA)
Conjugate
Non-conjugated
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of anti-SNAP29 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-SNAP29 antibody
SNAREs, soluble N-ethylmaleimide-sensitive factor-attachment protein receptors, are essential proteins for fusion of cellular membranes. SNAREs localized on opposing membranes assemble to form a trans-SNARE complex, an extended, parallel four alpha-helical bundle that drives membrane fusion. SNAP29 is a SNARE involved in autophagy through the direct control of autophagosome membrane fusion with the lysososome membrane. Plays also a role in ciliogenesis by regulating membrane fusions.
Applications Tested/Suitable for anti-SNAP29 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)

Western Blot (WB) of anti-SNAP29 antibody
Western blot
All lanes: SNAP29 antibody at 1.79 ug/ml
Lane 1: 293T whole cell lysate
Lane 2: Jurkat whole cell lysate
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 29 kDa
Observed band size: 29 kDa

anti-SNAP29 antibody Western Blot (WB) (WB) image
Immunohistochemistry (IHC) of anti-SNAP29 antibody
Immunohistochemistry of paraffin-embedded human kidney tissue using MBS7046564 at dilution 1:100
anti-SNAP29 antibody Immunohistochemistry (IHC) (IHC) image
Immunohistochemistry (IHC) of anti-SNAP29 antibody
Immunohistochemistry of paraffin-embedded human gastric cancer using MBS7046564 at dilution 1:100
anti-SNAP29 antibody Immunohistochemistry (IHC) (IHC) image
NCBI/Uniprot data below describe general gene information for SNAP29. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Related Accession #
Molecular Weight
28,970 Da
NCBI Official Full Name
synaptosomal-associated protein 29
NCBI Official Synonym Full Names
synaptosome associated protein 29
NCBI Official Symbol
SNAP29  [Similar Products]
NCBI Official Synonym Symbols
CEDNIK; SNAP-29
  [Similar Products]
NCBI Protein Information
synaptosomal-associated protein 29
UniProt Protein Name
Synaptosomal-associated protein 29
UniProt Synonym Protein Names
Soluble 29 kDa NSF attachment protein
Protein Family
UniProt Gene Name
SNAP29  [Similar Products]
UniProt Synonym Gene Names
SNAP-29  [Similar Products]
UniProt Entry Name
SNP29_HUMAN
NCBI Summary for SNAP29
This gene, a member of the SNAP25 gene family, encodes a protein involved in multiple membrane trafficking steps. Two other members of this gene family, SNAP23 and SNAP25, encode proteins that bind a syntaxin protein and mediate synaptic vesicle membrane docking and fusion to the plasma membrane. The protein encoded by this gene binds tightly to multiple syntaxins and is localized to intracellular membrane structures rather than to the plasma membrane. While the protein is mostly membrane-bound, a significant fraction of it is found free in the cytoplasm. Use of multiple polyadenylation sites has been noted for this gene. [provided by RefSeq, Jul 2008]
UniProt Comments for SNAP29
SNAP29: Involved in multiple membrane trafficking steps. Defects in SNAP29 are the cause of CEDNIK syndrome (CEDNIK). CEDNIK is a neurocutaneous syndrome characterized by cerebral dysgenesis, neuropathy, ichthyosis and palmoplantar keratoderma. Belongs to the SNAP-25 family.

Protein type: Vesicle

Chromosomal Location of Human Ortholog: 22q11.21

Cellular Component: centrosome; cytoplasm; Golgi membrane; plasma membrane; SNARE complex

Molecular Function: protein binding; SNAP receptor activity; syntaxin binding

Biological Process: cilium biogenesis; exocytosis; synaptic vesicle fusion to presynaptic membrane; synaptic vesicle priming; vesicle targeting

Disease: Cerebral Dysgenesis, Neuropathy, Ichthyosis, And Palmoplantar Keratoderma Syndrome
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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