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anti-SNRPD1 antibody :: Rabbit anti-Human SNRPD1 Polyclonal Antibody

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Catalog # MBS7006151
Unit / Price
Scan QR to view Datasheet
  0.05 mg  /  $160 +1 FREE 8GB USB
  0.1 mg  /  $235 +1 FREE 8GB USB
Product Name

SNRPD1, Polyclonal Antibody

Popular Item
Full Product Name

SNRPD1 Antibody

Product Synonym Names
Small nuclear ribonucleoprotein Sm D1; Sm-D1; Sm-D autoantigen; snRNP core protein D1; SNRPD1
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
OMIM
601063
3D Structure
ModBase 3D Structure for P62314
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Purity/Purification
>95%,Protein G purified
Form/Format
Liquid
Immunogen
Recombinant human Small nuclear ribonucleoprotein Sm D1 protein
Conjugation
Non-conjugated
Storage Buffer
Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-20822
Preparation and Storage
Shipped at 4 degree C. Upon delivery, aliquot and store at -20 degree C or -80 degree C.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of anti-SNRPD1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-SNRPD1 antibody
Core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs. Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in an heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP. May act as a charged protein scaffold to promote snRNP assembly or strengthen snRNP-snRNP interactions through nonspecific electrostatic contacts with RNA.
Applications Tested/Suitable for anti-SNRPD1 antibody
ELISA (EIA), Immunohistochemistry (IHC), Immunofluorescence (IF)

Immunohistochemistry (IHC) of anti-SNRPD1 antibody
Immunohistochemistry of paraffin-embedded human kidney tissue using MBS7006151 at dilution of 1:100
anti-SNRPD1 antibody Immunohistochemistry (IHC) (IHC) image
Immunofluorescence (IF) of anti-SNRPD1 antibody
Immunofluorescent analysis of PC3 cells using MBS7006151 at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
anti-SNRPD1 antibody Immunofluorescence (IF) image
Western Blot (WB) of anti-SNRPD1 antibody
Western Blot
Positive WB detected in: HEK293 whole cell lysate
All lanes: SNRPD1 antibody at 2.4ug/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 14 KDa
Observed band size: 14 KDa

anti-SNRPD1 antibody Western Blot (WB) (WB) image
NCBI/Uniprot data below describe general gene information for SNRPD1. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
13,282 Da
NCBI Official Full Name
small nuclear ribonucleoprotein Sm D1 isoform 2
NCBI Official Synonym Full Names
small nuclear ribonucleoprotein D1 polypeptide
NCBI Official Symbol
SNRPD1  [Similar Products]
NCBI Official Synonym Symbols
SMD1; SNRPD; Sm-D1; HsT2456
  [Similar Products]
NCBI Protein Information
small nuclear ribonucleoprotein Sm D1
UniProt Protein Name
Small nuclear ribonucleoprotein Sm D1
UniProt Synonym Protein Names
Sm-D autoantigen; snRNP core protein D1
UniProt Gene Name
SNRPD1  [Similar Products]
UniProt Synonym Gene Names
Sm-D1  [Similar Products]
UniProt Entry Name
SMD1_HUMAN
NCBI Summary for SNRPD1
This gene encodes a small nuclear ribonucleoprotein that belongs to the SNRNP core protein family. The protein may act as a charged protein scaffold to promote SNRNP assembly or strengthen SNRNP-SNRNP interactions through nonspecific electrostatic contacts with RNA. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2014]
UniProt Comments for SNRPD1
snRNP D1: May act as a charged protein scaffold to promote snRNP assembly or strengthen snRNP-snRNP interactions through nonspecific electrostatic contacts with RNA. Belongs to the snRNP core protein family.

Protein type: RNA splicing; Spliceosome; RNA-binding

Chromosomal Location of Human Ortholog: 18q11.2

Cellular Component: cytosol; nucleoplasm; nucleus; small nuclear ribonucleoprotein complex; snRNP U1; snRNP U2; snRNP U5; U12-dependent spliceosome

Molecular Function: protein binding; RNA binding

Biological Process: gene expression; nuclear mRNA splicing, via spliceosome; positive regulation of defense response to virus by host; RNA splicing; spliceosomal snRNP biogenesis; spliceosome assembly
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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