Q7Z7C7.1
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UniProt Primary Accession #
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UniProt Related Accession #
Molecular Weight
36,908 Da
NCBI Official Full Name
Stimulated by retinoic acid gene 8 protein homolog
NCBI Official Synonym Full Names
stimulated by retinoic acid 8
NCBI Protein Information
stimulated by retinoic acid gene 8 protein homolog; STRA8 {ECO:0000312|EMBL:AAP47163.1}; stimulated by retinoic acid 8 homolog; stimulated by retinoic acid gene 8 homolog
UniProt Protein Name
Stimulated by retinoic acid gene 8 protein homolog
UniProt Entry Name
STRA8_HUMAN
NCBI Summary for STRA8
This gene encodes a retinoic acid-responsive protein. A homologous protein in mouse has been shown to be involved in the regulation of meiotic initiation in both spermatogenesis and oogenesis, though feature differences between the mouse and human proteins suggest that these homologs are not entirely functionally equivalent. It is thought that this gene may play a role in spermatogenesis in humans. [provided by RefSeq, Nov 2010]
UniProt Comments for STRA8
STRA8: Meiosis-inducer required for the transition into meiosis for both female and male germ cells. In female germ cells, required for premeiotic DNA replication and subsequent events in meiotic prophase.
Chromosomal Location of Human Ortholog: 7q33
Cellular Component: cytoplasm; nucleus
Molecular Function: protein dimerization activity
Biological Process: fertilization; meiotic cell cycle DNA replication checkpoint; ovarian follicle development; meiotic chromosome condensation; meiotic recombination; synapsis; meiotic DNA double-strand break formation; spermatogenesis; regulation of organ growth; female meiosis sister chromatid cohesion; DNA replication; oocyte development
Research Articles on STRA8
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Products associated with anti-STRA8 antibody
Diseases associated with anti-STRA8 antibody
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