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anti-MMP10 antibody :: Rabbit anti-Human Stromelysin-2 Polyclonal Antibody

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Catalog # MBS7003620
Unit / Price
Scan QR to view Datasheet
  0.05 mg  /  $160 +1 FREE 8GB USB
  0.1 mg  /  $235 +1 FREE 8GB USB
Product Name

Stromelysin-2 (MMP10), Polyclonal Antibody

Popular Item
Full Product Name

Rabbit anti-Human Stromelysin-2 polyclonal Antibody

Product Synonym Names
Matrix metalloproteinase-10; Transin-2; MMP10; STMY2
Product Synonym Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
OMIM
185260
3D Structure
ModBase 3D Structure for P09238
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Purity/Purification
Caprylic Acid Ammonium Sulfate Precipitation purified
Form/Format
Liquid
Immunogen
Recombinant human Stromelysin-2 protein
Conjugation
Non-conjugated
Storage Buffer
Preservative: 0.03% Proclin 300; Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-26694 / sc-26696 / sc-6842 / sc-9941
Preparation and Storage
Shipped at 4 degree C. Upon delivery, aliquot and store at -20 degree C or -80 degree C.
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of anti-MMP10 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-MMP10 antibody
Can degrade fibronectin, gelatins of type I, III, IV, and V; weakly collagens III, IV, and V. Activates procollagenase.

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP s are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades proteoglycans and fibronectin. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3.
Product Categories/Family for anti-MMP10 antibody
Applications Tested/Suitable for anti-MMP10 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-MMP10 antibody
Recommended dilution: WB:1:500-2000, IHC:1:20-1:200

Western Blot (WB) of anti-MMP10 antibody
All lanes: Stromelysin-2 antibody at 2ug/ml+mouse kidney tissue
Secondary
Goat polyclonal to Rabbit IgG at 1/10000 dilution
Predicted band size: 54kDa
Observed band size: 54 kDa

anti-MMP10 antibody Western Blot (WB) (WB) image
Immunohistochemistry (IHC) of anti-MMP10 antibody
Immunohistochemistry of paraffin-embedded human kidney using MBS7003620 at dilution of 1:50
anti-MMP10 antibody Immunohistochemistry (IHC) (IHC) image
Western Blot (WB) of anti-MMP10 antibody
Western Blot
Positive WB detected in: mouse heart
All lanes: MMP10 antibody at 4.5ug/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 54 kDa
Observed band size: 54 kDa

anti-MMP10 antibody Western Blot (WB) (WB) image
Immunofluorescence (IF) of anti-MMP10 antibody
Immunofluorescent analysis of HepG2 cells using MBS7003620 at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
anti-MMP10 antibody Immunofluorescence (IF) image
NCBI/Uniprot data below describe general gene information for MMP10. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
54,151 Da[Similar Products]
NCBI Official Full Name
stromelysin-2 preproprotein
NCBI Official Synonym Full Names
matrix metallopeptidase 10
NCBI Official Symbol
MMP10  [Similar Products]
NCBI Official Synonym Symbols
SL-2; STMY2
  [Similar Products]
NCBI Protein Information
stromelysin-2
UniProt Protein Name
Stromelysin-2
UniProt Synonym Protein Names
Matrix metalloproteinase-10; MMP-10; Transin-2
Protein Family
UniProt Gene Name
MMP10  [Similar Products]
UniProt Synonym Gene Names
STMY2; SL-2; MMP-10  [Similar Products]
UniProt Entry Name
MMP10_HUMAN
NCBI Summary for MMP10
This gene encodes a member of the peptidase M10 family of matrix metalloproteinases (MMPs). Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. The encoded preproprotein is proteolytically processed to generate the mature protease. This secreted protease breaks down fibronectin, laminin, elastin, proteoglycan core protein, gelatins, and several types of collagen. The gene is part of a cluster of MMP genes on chromosome 11. [provided by RefSeq, Jan 2016]
UniProt Comments for MMP10
MMP10: Can degrade fibronectin, gelatins of type I, III, IV, and V; weakly collagens III, IV, and V. Activates procollagenase. Belongs to the peptidase M10A family.

Protein type: Secreted; EC 3.4.24.22; Secreted, signal peptide; Protease; Extracellular matrix

Chromosomal Location of Human Ortholog: 11q22.3

Cellular Component: extracellular region; extracellular space; proteinaceous extracellular matrix

Molecular Function: calcium ion binding; metalloendopeptidase activity; zinc ion binding

Biological Process: collagen catabolic process; extracellular matrix disassembly; extracellular matrix organization and biogenesis; proteolysis; regulation of cell migration
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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