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anti-TAC1 antibody :: Rabbit anti-Human TAC1 Polyclonal Antibody

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Catalog # MBS6009007
Unit / Price
  0.2 mL  /  $550 +1 FREE 8GB USB
anti-TAC1 antibody
Product Name

TAC1, Polyclonal Antibody

Also Known As

TAC1, CT (TAC1, NKA, NKNA, TAC2, Protachykinin-1, PPT, Substance P, Neurokinin A, Neuromedin L, Substance K, Neuropeptide K, Neuropeptide gamma, C-terminal-flanking peptide)

Product Synonym Names
Anti -TAC1, CT (TAC1, NKA, NKNA, TAC2, Protachykinin-1, PPT, Substance P, Neurokinin A, Neuromedin L, Substance K, Neuropeptide K, Neuropeptide gamma, C-terminal-flanking peptide)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Chromosome Location
Chromosome: 7; NC_000007.13 (97361271..97369784). Location: 7q21-q22
OMIM
162320
3D Structure
ModBase 3D Structure for P20366
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Specificity
Human
Purity/Purification
Affinity Purified
Purified by Protein A affinity chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Immunogen
TAC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 109-137 amino acids from the C-terminal region of human TAC1.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Other Notes
Small volumes of anti-TAC1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Product Categories/Family for anti-TAC1 antibody
Applications Tested/Suitable for anti-TAC1 antibody
ELISA (EL/EIA), Western Blot (WB), Flow Cytometry (FC/FACS)
Application Notes for anti-TAC1 antibody
Suitable for use in Western Blot, Flow Cytometry, ELISA
Dilution: ELISA: 1:1,000
Western Blot: 1:100-500
Flow Cytometry: 1:10-50
NCBI/Uniprot data below describe general gene information for TAC1. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
15,003 Da[Similar Products]
NCBI Official Full Name
TAC1
NCBI Official Synonym Full Names
tachykinin, precursor 1
NCBI Official Symbol
NCBI Official Synonym Symbols
NK2; NPK; NKNA; TAC2; Hs.2563
  [Similar Products]
NCBI Protein Information
protachykinin-1; PPT; substance K; substance P; neurokinin 1; neurokinin 2; neurokinin A; neuromedin L; tachykinin 2; neuropeptide K; neurokinin alpha; preprotachykinin; neuropeptide gamma; tachykinin, precursor 1 (substance K, substance P, neurokinin 1, neurokinin 2, neuromedin L, neurokinin alpha, neuropeptide K, neuropeptide gamma)
UniProt Protein Name
Protachykinin-1
UniProt Synonym Protein Names
PPTCleaved into the following 5 chains:Substance PNeurokinin A; NKA; Alternative name(s):; Neuromedin L; Substance K
Protein Family
UniProt Gene Name
UniProt Synonym Gene Names
NKA; NKNA; TAC2; NKA; NPK  [Similar Products]
UniProt Entry Name
TKN1_HUMAN
NCBI Summary for TAC1
This gene encodes four products of the tachykinin peptide hormone family, substance P and neurokinin A, as well as the related peptides, neuropeptide K and neuropeptide gamma. These hormones are thought to function as neurotransmitters which interact with nerve receptors and smooth muscle cells. They are known to induce behavioral responses and function as vasodilators and secretagogues. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
UniProt Comments for TAC1
TAC1: Tachykinins are active peptides which excite neurons, evoke behavioral responses, are potent vasodilators and secretagogues, and contract (directly or indirectly) many smooth muscles. Belongs to the tachykinin family. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 7q21-q22

Cellular Component: extracellular space; cell soma; axon; extracellular region; plasma membrane

Molecular Function: protein binding; substance P receptor binding

Biological Process: tachykinin signaling pathway; negative regulation of heart rate; insemination; response to hormone stimulus; response to morphine; response to lipopolysaccharide; response to pain; sensory perception of pain; positive regulation of saliva secretion; synaptic transmission; elevation of cytosolic calcium ion concentration; cell-cell signaling; positive regulation of lymphocyte proliferation; positive regulation of acute inflammatory response; neuropeptide signaling pathway; regulation of blood pressure; positive regulation of stress fiber formation; positive regulation of action potential; inflammatory response; associative learning; detection of abiotic stimulus; positive regulation of synaptic transmission, cholinergic; positive regulation of synaptic transmission, GABAergic; positive regulation of ossification; long-term memory
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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