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anti-TAF5 antibody :: Rabbit anti-Human TAF5 Polyclonal Antibody

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Catalog # MBS7045320
Unit / Price
  0.05 mL  /  $120 +1 FREE 8GB USB
  0.1 mL  /  $160 +1 FREE 8GB USB
Product Name

TAF5, Polyclonal Antibody

Popular Item
Also Known As

TAF5 Antibody

Product Synonym Names
Transcription initiation factor TFIID subunit 5; Transcription initiation factor TFIID 100 kDa subunit; TAF(II)100; TAFII-100; TAFII100; TAF5; TAF2D
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence Length
800
OMIM
601787
3D Structure
ModBase 3D Structure for Q15542
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Purity/Purification
Antigen Affinity Purified
Form/Format
Liquid
Species
Human
Immunogen
Recombinant human Transcription initiation factor TFIID subunit 5 protein (C-145AA)
Conjugate
Non-conjugated
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-109058 / sc-98823
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of anti-TAF5 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-TAF5 antibody
TAFs are components of the transcription factor IID (TFIID) complex, PCAF histone acetylase complex and TBP-free TAFII complex (TFTC). TAFs components-TIIFD are essential for mediating regulation of RNA polymerase transcription. TAF5/TAFII100 interacts strongly with the histone H4-related TAF6/TAFII80 and the histone H3-related TAF9/TAFII31, as well as a stable complex comprised of both TAF5/TAFII80 and TAF6/TAFII31. Apparently weaker interactions of TAF5/TAFII100 with TBP, TAF1/TAFII250, TAF11/TAFII28, and TAF12/TAFII20, but not TAF7/TAFII55, also have been observed.
Applications Tested/Suitable for anti-TAF5 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)

Western Blot (WB) of anti-TAF5 antibody
Western blot
All lanes: TAF5 antibody at 1.74 ug/ml
Lane 1: Jurkat whole cell lysate
Lane 2: MCF7 whole cell lysate
Secondary
Goat polyclonal to Rabbit IgG at 1/10000 dilution
Predicted band size: 87,81 kDa
Observed band size: 87 kDa,40 kDa,51 kDa

anti-TAF5 antibody Western Blot (WB) (WB) image
Immunohistochemistry (IHC) of anti-TAF5 antibody
Immunohistochemistry of paraffin-embedded human liver cancer using MBS7045320 at dilution 1:100
anti-TAF5 antibody Immunohistochemistry (IHC) (IHC) image
NCBI/Uniprot data below describe general gene information for TAF5. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
80,508 Da
NCBI Official Full Name
transcription initiation factor TFIID subunit 5 isoform 1
NCBI Official Synonym Full Names
TATA-box binding protein associated factor 5
NCBI Official Symbol
NCBI Official Synonym Symbols
TAF2D; TAFII100; TAFII-100; TAF(II)100
  [Similar Products]
NCBI Protein Information
transcription initiation factor TFIID subunit 5
UniProt Protein Name
Transcription initiation factor TFIID subunit 5
UniProt Synonym Protein Names
Transcription initiation factor TFIID 100 kDa subunit; TAF(II)100; TAFII-100; TAFII100
UniProt Gene Name
UniProt Synonym Gene Names
TAF2D; TAF(II)100; TAFII-100; TAFII100  [Similar Products]
UniProt Entry Name
TAF5_HUMAN
NCBI Summary for TAF5
Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes an integral subunit of TFIID associated with all transcriptionally competent forms of that complex. This subunit interacts strongly with two TFIID subunits that show similarity to histones H3 and H4, and it may participate in forming a nucleosome-like core in the TFIID complex. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]
UniProt Comments for TAF5
TAF5: TAFs are components of the transcription factor IID (TFIID) complex, PCAF histone acetylase complex and TBP-free TAFII complex (TFTC). TAFs components-TIIFD are essential for mediating regulation of RNA polymerase transcription. TAF5/TAFII100 interacts strongly with the histone H4-related TAF6/TAFII80 and the histone H3-related TAF9/TAFII31, as well as a stable complex comprised of both TAF5/TAFII80 and TAF6/TAFII31. Apparently weaker interactions of TAF5/TAFII100 with TBP, TAF1/TAFII250, TAF11/TAFII28, and TAF12/TAFII20, but not TAF7/TAFII55, also have been observed. Belongs to the WD repeat TAF5 family. 2 isoforms of the human protein are produced by alternative splicing.

Chromosomal Location of Human Ortholog: 10q24-q25.2

Cellular Component: actin cytoskeleton; intracellular membrane-bound organelle; nucleolus; nucleoplasm; nucleus; transcription factor TFIID complex

Molecular Function: histone acetyltransferase activity; protein binding; protein dimerization activity; transcription factor activity

Biological Process: chromatin modification; RNA elongation from RNA polymerase II promoter; snRNA transcription from RNA polymerase II promoter; transcription from RNA polymerase II promoter; transcription initiation; transcription initiation from RNA polymerase II promoter
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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