• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

anti-TNFAIP8 antibody :: Rabbit anti-Human TNFAIP8 Polyclonal Antibody

Scan QR to view Datasheet
Catalog # MBS7044940
Unit / Price
  0.05 mL  /  $120 +1 FREE 8GB USB
  0.1 mL  /  $160 +1 FREE 8GB USB
Product Name

TNFAIP8, Polyclonal Antibody

Popular Item
Also Known As

TNFAIP8 Antibody

Product Synonym Names
Tumor necrosis factor alpha-induced protein 8; TNF alpha-induced protein 8; Head and neck tumor and metastasis-related protein; MDC-3.13; NF-kappa-B-inducible DED-containing protein; NDED; SCC-S2; TNF-induced protein GG2-1; TNFAIP8
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence Length
188
OMIM
612111
3D Structure
ModBase 3D Structure for O95379
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Purity/Purification
Antigen Affinity Purified
Form/Format
Liquid
Species
Human
Immunogen
Recombinant human Tumor necrosis factor alpha-induced protein 8 protein (1-198AA)
Conjugate
Non-conjugated
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-82054
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of anti-TNFAIP8 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-TNFAIP8 antibody
Acts as a negative mediator of apoptosis and may play a role in tumor progression. Suppresses the TNF-mediated apoptosis by inhibiting caspase-8 activity but not the processing of procaspase-8, subsequently resulting in inhibition of BID cleavage and caspase-3 activation.
Applications Tested/Suitable for anti-TNFAIP8 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)

Western Blot (WB) of anti-TNFAIP8 antibody
Western blot
All lanes:  TNFAIP8antibody at 2.32ug/ml
Lane 1 : A431 whole cell lysate
Lane 2 : PC-3 whole cell lysate
Secondary
Goat polyclonal to Rabbit IgG at 1/10000 dilution
Predicted band size: 24,23,22,25 kDa
Observed band size: 23 kDa

anti-TNFAIP8 antibody Western Blot (WB) (WB) image
Immunohistochemistry (IHC) of anti-TNFAIP8 antibody
Immunohistochemistry of paraffin-embedded human colon cancer using MBS7044940 at dilution 1:100
anti-TNFAIP8 antibody Immunohistochemistry (IHC) (IHC) image
Immunohistochemistry (IHC) of anti-TNFAIP8 antibody
Immunohistochemistry of paraffin-embedded human breast cancer using MBS7044940 at dilution 1:100
anti-TNFAIP8 antibody Immunohistochemistry (IHC) (IHC) image
NCBI/Uniprot data below describe general gene information for TNFAIP8. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
24,385 Da
NCBI Official Full Name
tumor necrosis factor alpha-induced protein 8 isoform b
NCBI Official Synonym Full Names
TNF alpha induced protein 8
NCBI Official Symbol
TNFAIP8  [Similar Products]
NCBI Official Synonym Symbols
NDED; GG2-1; SCCS2; SCC-S2; MDC-3.13
  [Similar Products]
NCBI Protein Information
tumor necrosis factor alpha-induced protein 8
UniProt Protein Name
Tumor necrosis factor alpha-induced protein 8
UniProt Synonym Protein Names
Head and neck tumor and metastasis-related protein; MDC-3.13; NF-kappa-B-inducible DED-containing protein; NDED; SCC-S2; TNF-induced protein GG2-1
UniProt Gene Name
TNFAIP8  [Similar Products]
UniProt Synonym Gene Names
TNF alpha-induced protein 8; NDED  [Similar Products]
UniProt Entry Name
TFIP8_HUMAN
UniProt Comments for TNFAIP8
TNFAIP8: Acts as a negative mediator of apoptosis and may play a role in tumor progression. Suppresses the TNF-mediated apoptosis by inhibiting caspase-8 activity but not the processing of procaspase-8, subsequently resulting in inhibition of BID cleavage and caspase-3 activation. Belongs to the TNFAIP8 family. 3 isoforms of the human protein are produced by alternative splicing.

Chromosomal Location of Human Ortholog: 5q23.1

Cellular Component: cytoplasm

Molecular Function: caspase inhibitor activity; protein binding

Biological Process: negative regulation of apoptosis
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000