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anti-TRH antibody :: Rabbit anti-Human TRH TRH Polyclonal Antibody

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Catalog # MBS534472
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anti-TRH antibody
Product Name

TRH, Polyclonal Antibody

Popular Item
Full Product Name

TRH antibody

Product Synonym Names
Polyclonal TRH; Anti-TRH; Thyrotropin Releasing Hormone
Product Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for P20396
Species Reactivity
Human TRH
Supplied as whole antiserum containing 0.09% NaN3. Dilute in PBS immediately before use.
Biological Significance
Thyrotropin Releasing Hormone is produced in thehypothalamus and stimulates the release of ThyroidStimulating Hormone (TSH) in the pituitary.
Biohazard Information
This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling this product.
TRH antibody was raised in rabbit using a synthetic peptide conjugated with KLH as the immunogen.
Preparation and Storage
Store at 4 degree C for short term storage. Aliquot and store at -20 degree C for long term storage. Avoid repeated freeze/thaw cycles.
Other Notes
Small volumes of anti-TRH antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-TRH antibody
Rabbit polyclonal TRH antibody
Product Categories/Family for anti-TRH antibody
Applications Tested/Suitable for anti-TRH antibody
Immunocytochemistry (ICC), Immunohistochemistry (IHC)
Application Notes for anti-TRH antibody
IHC: 1:50
NCBI/Uniprot data below describe general gene information for TRH. It may not necessarily be applicable to this product.
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
27,404 Da
NCBI Official Full Name
thyrotropin releasing hormone preproprotein
NCBI Official Synonym Full Names
thyrotropin-releasing hormone
NCBI Official Symbol
NCBI Official Synonym Symbols
  [Similar Products]
NCBI Protein Information
thyrotropin releasing hormone
UniProt Protein Name
Pro-thyrotropin-releasing hormone
UniProt Synonym Protein Names
UniProt Gene Name
UniProt Synonym Gene Names
Pro-TRH; TRH; TRF  [Similar Products]
UniProt Entry Name
NCBI Summary for TRH
This gene encodes a member of the thyrotropin-releasing hormone family. Cleavage of the encoded proprotein releases mature thyrotropin-releasing hormone, which is a tripeptide hypothalamic regulatory hormone. The human proprotein contains six thyrotropin-releasing hormone tripeptides. Thyrotropin-releasing hormone is involved in the regulation and release of thyroid-stimulating hormone, as well as prolactin. Deficiency of this hormone has been associated with hypothalamic hypothyroidism. [provided by RefSeq, May 2013]
UniProt Comments for TRH
TRH: Functions as a regulator of the biosynthesis of TSH in the anterior pituitary gland and as a neurotransmitter/ neuromodulator in the central and peripheral nervous systems. May promote hair shaft elongation, prolonge the hair cycle growth phase (anagen) and antagonized its termination by TGFB2. May also increase proliferation and inhibited apoptosis of hair matrix keratinocytes. Belongs to the TRH family.

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 3q13.3-q21

Cellular Component: plasma membrane; extracellular region; nucleus; secretory granule

Molecular Function: neuropeptide hormone activity; thyrotropin-releasing hormone activity

Biological Process: hormone-mediated signaling; negative regulation of glutamate secretion; eating behavior; positive regulation of insulin secretion; histamine metabolic process; signal transduction; adult walking behavior; response to ethanol; cell-cell signaling; response to glucose stimulus; response to hypoxia; response to cold; positive regulation of gamma-aminobutyric acid secretion; response to corticosterone stimulus

Disease: Thyrotropin-releasing Hormone Deficiency
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While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

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Organs/Tissues associated with anti-TRH antibody
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