• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

anti-TPSb2 antibody :: Rabbit anti-Human Tryptase Beta 2 (TPSb2) Polyclonal Antibody

Scan QR to view Datasheet
Catalog # MBS2005823 (SPECIAL PROMOTION: Get FREE $5 Starbucks gift card (Maximum 5 gift cards/product). Gift card(s) will be included with shipment)
Unit / Price
  0.01 mg  /  $115 +1 FREE 8GB USB
  0.02 mg  /  $135 +1 FREE 8GB USB
  0.05 mg  /  $190 +1 FREE 8GB USB
  0.1 mg  /  $245 +1 FREE 8GB USB
  0.2 mg  /  $370 +1 FREE 8GB USB
  1 mg  /  $880 +1 FREE 8GB USB
Western Blot (WB)
Product Name

Tryptase Beta 2 (TPSb2), Polyclonal Antibody

Popular Item
Also Known As

Biotin-Linked Antibody to Tryptase Beta 2 (TPSb2)

Matching Pairs
Unconjugated Antibody: Tryptase Beta 2 (TPSb2) (MBS2004625)
Biotin Conjugated Antibody: Tryptase Beta 2 (TPSb2) (MBS2005823)
Matching Pairs
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence Length
Chromosome Location
Chromosome: 16; NC_000016.9 (1278336..1280185, complement). Location: 16p13.3
3D Structure
ModBase 3D Structure for P20231
Species Reactivity
The antibody is a rabbit polyclonal antibody raised against TPSb2. It has been selected for its ability to recognize TPSb2 in immunohistochemical staining and western blotting.
Affinity Chromatography
Supplied as solution form in PBS, pH7.4, containing 0.02% NaN3,50% glycerol.
200ug/ml (lot specific)
TPSb2, Human
Immunogen Information
Recombinant TPSb2 (Gln35~Pro275) with N-terminal His-Tag expressed in E.coli.
Accession No.
Unconjugated Antibody
The unconjugated antibody version of this item is also available as catalog #MBS2004625
Preparation and Storage
Store at 4 degree C for frequent use. Stored at -20 degree C to -80 degree C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.
Other Notes
Small volumes of anti-TPSb2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Product Categories/Family for anti-TPSb2 antibody
Applications Tested/Suitable for anti-TPSb2 antibody
Immunohistochemistry (IHC), ELISA (EIA), Western Blot (WB)
Application Notes for anti-TPSb2 antibody
Western blotting: 1:50-400
Immunocytochemistry in formalin fixed cells: 1:50-500
Immunohistochemistry in formalin fixed frozen section: 1:50-500
Immunohistochemistry in paraffin section: 1:10-100
Enzyme-linked Immunosorbent Assay: 1:100-200
Optimal working dilutions must be determined by end user.

Western Blot (WB) of anti-TPSb2 antibody
(Figure. Western Blot; Sample: Recombinant protein.)
anti-TPSb2 antibody Western Blot (WB) (WB) image
NCBI/Uniprot data below describe general gene information for TPSb2. It may not necessarily be applicable to this product.
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
tryptase beta-2
NCBI Official Synonym Full Names
tryptase beta 2 (gene/pseudogene)
NCBI Official Symbol
TPSB2  [Similar Products]
NCBI Official Synonym Symbols
TPS2; tryptaseB; tryptaseC
  [Similar Products]
NCBI Protein Information
tryptase beta-2; mast cell tryptase beta II; mast cell tryptase beta III
UniProt Protein Name
Tryptase beta-2
UniProt Synonym Protein Names
Tryptase II
Protein Family
UniProt Gene Name
TPSB2  [Similar Products]
UniProt Synonym Gene Names
TPS2; Tryptase-2  [Similar Products]
UniProt Entry Name
NCBI Summary for TPSb2
Tryptases comprise a family of trypsin-like serine proteases, the peptidase family S1. Tryptases are enzymatically active only as heparin-stabilized tetramers, and they are resistant to all known endogenous proteinase inhibitors. Several tryptase genes are clustered on chromosome 16p13.3. These genes are characterized by several distinct features. They have a highly conserved 3' UTR and contain tandem repeat sequences at the 5' flank and 3' UTR which are thought to play a role in regulation of the mRNA stability. These genes have an intron immediately upstream of the initiator Met codon, which separates the site of transcription initiation from protein coding sequence. This feature is characteristic of tryptases but is unusual in other genes. The alleles of this gene exhibit an unusual amount of sequence variation, such that the alleles were once thought to represent two separate genes, beta II and beta III. Beta tryptases appear to be the main isoenzymes expressed in mast cells, whereas in basophils, alpha-tryptases predominate. Tryptases have been implicated as mediators in the pathogenesis of asthma and other allergic and inflammatory disorders. [provided by RefSeq, Jul 2008]
UniProt Comments for TPSb2
TPSB2: Tryptase is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type. Has an immunoprotective role during bacterial infection. Required to efficiently combat K.pneumoniae infection. Belongs to the peptidase S1 family. Tryptase subfamily.

Protein type: Protease; EC; Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 16p13.3

Cellular Component: extracellular region

Molecular Function: protein binding; serine-type peptidase activity; serine-type endopeptidase activity

Biological Process: proteolysis
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Products associated withanti-TPSb2 antibody
 Reference Product  PubMed Publications
 TPSAB1 antibody  >4 publications with TPSb2 and TPSAB1
Diseases associated with anti-TPSb2 antibody
Organs/Tissues associated with anti-TPSb2 antibody
 Organ/Tissue Name  Pubmed Publications
 Bone Antibodies  >1 publications with TPSb2 and Bone
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

Contact Us

Please fill out the form below and our representative will get back to you shortly.