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anti-TNFRSF1A antibody :: Rabbit anti-Human Tumor Necrosis Factor Receptor Superfamily Polyclonal Antibody

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Catalog # MBS2027735 (SPECIAL PROMOTION: Get FREE $5 Starbucks gift card (Maximum 5 gift cards/product). Gift card(s) will be included with shipment)
Unit / Price
  0.01 mg  /  $90 +1 FREE 8GB USB
  0.02 mg  /  $105 +1 FREE 8GB USB
  0.05 mg  /  $135 +1 FREE 8GB USB
  0.1 mg  /  $165 +1 FREE 8GB USB
  0.2 mg  /  $230 +1 FREE 8GB USB
  1 mg  /  $520 +1 FREE 8GB USB
Product Name

Tumor Necrosis Factor Receptor Superfamily (TNFRSF1A), Polyclonal Antibody

Popular Item
Also Known As

Polyclonal Antibody to Tumor Necrosis Factor Receptor Superfamily, Member 1A (TNFRSF1A)

Matching Pairs
Unconjugated Antibody: Tumor Necrosis Factor Receptor Superfamily (MBS2027735)
APC-CY7 Conjugated Secondary Antibody: Immunoglobulin G (MBS2090675)
Matching Pairs
Unconjugated Antibody: Tumor Necrosis Factor Receptor Superfamily (MBS2027735)
Unconjugated Secondary Antibody: Immunoglobulin G (MBS2090678)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence
Antigen: The target protein is fused with two N-terminal Tags, His-tag and T7-tag and its sequence is listed below.
MGSSHHHHHH SSGLVPRGSH MASMTGGQQM GRGS- CGK STPEKEGELE GTTTKPLAPN PSFSPTPGFT PTLGFSPVPS STFTSSSTYT PGDCPNFAAP RREVAPPYQG ADPILATALA SDPIPNPLQK WEDSAHKPQS LDTDDPATLY AVVENVPPLR WKEFVRRLGL SDHEIDRLEL
OMIM
M58286 mRNA
3D Structure
ModBase 3D Structure for P19438
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Specificity
The antibody is a rabbit polyclonal antibody raised against TNFRSF1A. It has beenselected for its ability to recognize TNFRSF1A in immunohistochemical staining andwestern blotting.
Purity/Purification
Affinity Chromatography
Form/Format
Liquid
Concentration
200ug/ml (lot specific)
Fragment
TNFRSF1A (Cys248~Met428)
Organism Species
Homo sapiens (Human)
Conjugate
No Conjugate
Immunogen
Recombinant TNFRSF1A (Cys248~Met428) expressed in E Coli.
Conjugated Antibody
The APC conjugated antibody version of this item is also available as catalog #MBS2055948
Preparation and Storage
Store at 4 degree C for frequent use. Stored at -20 degree C to -80 degree C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.
Other Notes
Small volumes of anti-TNFRSF1A antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-TNFRSF1A antibody
Western Blot (WB), Immunocytochemistry (ICC), Immunohistochemistry (IHC) Formalin/Paraffin, ELISA (EIA)
Application Notes for anti-TNFRSF1A antibody
Western blotting: 0.5-5ug/mL
Immunocytochemistry in formalin fixed cells: 5-20ug/mL
Immunohistochemistry in formalin fixed frozen section: 5-20ug/mL
Immunohistochemistry in paraffin section: 5-20ug/mL
Optimal working dilutions must be determined by end user.

Western Blot (WB) Knockout Verification of anti-TNFRSF1A antibody
Knockout Verification: Lane 1: Wild-type Hela cell lysate; Lane 2: TNFRSF1A knockout Hela cell lysate; Predicted MW: 50,38,25kDa Observed MW: 23kDa Primary Ab: 3ug/ml Rabbit Anti-Human TNFRSF1A Antibody Second Ab: 0.2ug/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody
anti-TNFRSF1A antibody Western Blot (WB) Knockout Verification (WB) image
Western Blot (WB) of anti-TNFRSF1A antibody
Western Blot; Sample: Lane1: Human Hela Cells; Lane2: Human Jurkat Cells.
anti-TNFRSF1A antibody Western Blot (WB) (WB) image
Western Blot (WB) of anti-TNFRSF1A antibody
Western Blot; Sample: Recombinant TNFRSF1A, Human.
anti-TNFRSF1A antibody Western Blot (WB) (WB) image
Immunohistochemistry (IHC) of anti-TNFRSF1A antibody
FITC staining on IHC-P Simple: Hela cells)
anti-TNFRSF1A antibody Immunohistochemistry (IHC) (IHC) image
Immunohistochemistry (IHC) of anti-TNFRSF1A antibody
DAB staining on IHC-P; Samples: Human Kidney Tissue
anti-TNFRSF1A antibody Immunohistochemistry (IHC) (IHC) image
Immunohistochemistry (IHC) of anti-TNFRSF1A antibody
DAB staining on IHC-P; Samples: Human Lung Cancer Tissue
anti-TNFRSF1A antibody Immunohistochemistry (IHC) (IHC) image
Immunohistochemistry (IHC) of anti-TNFRSF1A antibody
DAB staining on IHC-P; Samples: Human Brain Tissue.
anti-TNFRSF1A antibody Immunohistochemistry (IHC) (IHC) image
NCBI/Uniprot data below describe general gene information for TNFRSF1A. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
24,194 Da
NCBI Official Full Name
tumor necrosis factor receptor superfamily member 1A isoform 1
NCBI Official Synonym Full Names
TNF receptor superfamily member 1A
NCBI Official Symbol
TNFRSF1A  [Similar Products]
NCBI Official Synonym Symbols
FPF; p55; p60; TBP1; TNF-R; TNFAR; TNFR1; p55-R; CD120a; TNFR55; TNFR60; TNF-R-I; TNF-R55
  [Similar Products]
NCBI Protein Information
tumor necrosis factor receptor superfamily member 1A
UniProt Protein Name
Tumor necrosis factor receptor superfamily member 1A
UniProt Synonym Protein Names
Tumor necrosis factor receptor 1; TNF-R1
UniProt Gene Name
TNFRSF1A  [Similar Products]
UniProt Synonym Gene Names
TNFAR; TNFR1; TNF-R1; TNF-RI; TNFR-I; TBPI  [Similar Products]
NCBI Summary for TNFRSF1A
This gene encodes a member of the TNF receptor superfamily of proteins. The encoded receptor is found in membrane-bound and soluble forms that interact with membrane-bound and soluble forms, respectively, of its ligand, tumor necrosis factor alpha. Binding of membrane-bound tumor necrosis factor alpha to the membrane-bound receptor induces receptor trimerization and activation, which plays a role in cell survival, apoptosis, and inflammation. Proteolytic processing of the encoded receptor results in release of the soluble form of the receptor, which can interact with free tumor necrosis factor alpha to inhibit inflammation. Mutations in this gene underlie tumor necrosis factor receptor-associated periodic syndrome (TRAPS), characterized by fever, abdominal pain and other features. Mutations in this gene may also be associated with multiple sclerosis in human patients. [provided by RefSeq, Sep 2016]
UniProt Comments for TNFRSF1A
Receptor for TNFSF2/TNF-alpha and homotrimeric TNFSF1/lymphotoxin-alpha. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Contributes to the induction of non-cytocidal TNF effects including anti-viral state and activation of the acid sphingomyelinase.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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