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anti-VAMP7 antibody :: Rabbit anti-Human Vesicle-associated membrane protein 7 Polyclonal Antibody

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Catalog # MBS7001233
Unit / Price
  0.05 mg  /  $160 +1 FREE 8GB USB
  0.1 mg  /  $235 +1 FREE 8GB USB
Product Name

Vesicle-associated membrane protein 7 (VAMP7), Polyclonal Antibody

Popular Item
Full Product Name

Rabbit anti-human Vesicle-associated membrane protein 7 polyclonal Antibody

Product Synonym Names
Synaptobrevin-like protein 1; Tetanus-insensitive VAMP
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
OMIM
300053
3D Structure
ModBase 3D Structure for P51809
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Purity/Purification
Caprylic Acid Ammonium Sulfate Precipitation purified
Form/Format
Liquid
Immunogen
Recombinant human Vesicle-associated membrane protein 7 protein
Conjugation
Non-conjugated
Storage Buffer
Preservative: 0.03% Proclin 300; Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-32592 / sc-32593 / sc-67060
Preparation and Storage
Shipped at 4 degree C. Upon delivery, aliquot and store at -20 degree C or -80 degree C.
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of anti-VAMP7 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-VAMP7 antibody
Involved in the targeting and/or fusion of transport vesicles to their target membrane during transport of proteins from the early endosome to the lysosome. Required for heterotypic fusion of late endosomes with lysosomes and homotypic lysosomal fusion. Required for calcium regulated lysosomal exocytosis. Involved in the export of chylomicrons from the endoplasmic reticulum to the cis Golgi. Required for exocytosis of mediators during eosinophil and neutrophil degranulation, and target cell killing by natural killer cells. Required for focal exocytosis of late endocytic vesicles during phagosome formation.
Product Categories/Family for anti-VAMP7 antibody
Applications Tested/Suitable for anti-VAMP7 antibody
ELISA (EIA), Immunohistochemistry (IHC)
Application Notes for anti-VAMP7 antibody
Recommended dilution: IHC: 1:20-1:200

Immunohistochemistry (IHC) of anti-VAMP7 antibody
Immunohistochemistry of paraffin-embeded human colorectal carcinoma using MBS7001233 at dilution of 1:100
anti-VAMP7 antibody Immunohistochemistry (IHC) (IHC) image
Western Blot (WB) of anti-VAMP7 antibody
Western Blot
Positive WB detected in: Mouse brain tissue,Mouse liver tissue,Mouse kidney tissue
All lanes: VAMP7 antibody at 2ug/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 25 KDa
Observed band size: 25 KDa

anti-VAMP7 antibody Western Blot (WB) (WB) image
Immunohistochemistry (IHC) of anti-VAMP7 antibody
Immunohistochemistry of paraffin-embedded human lung tissue using MBS7001233 at dilution of 1:100
anti-VAMP7 antibody Immunohistochemistry (IHC) (IHC) image
Immunohistochemistry (IHC) of anti-VAMP7 antibody
Immunohistochemistry of paraffin-embedded human small intestine tissue using MBS7001233 at dilution of 1:100
anti-VAMP7 antibody Immunohistochemistry (IHC) (IHC) image
Immunofluorescence (IF) of anti-VAMP7 antibody
Immunofluorescent analysis of HepG2 cells using MBS7001233 at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
anti-VAMP7 antibody Immunofluorescence (IF) image
NCBI/Uniprot data below describe general gene information for VAMP7. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
20,121 Da
NCBI Official Full Name
vesicle-associated membrane protein 7 isoform 2
NCBI Official Synonym Full Names
vesicle associated membrane protein 7
NCBI Official Symbol
VAMP7  [Similar Products]
NCBI Official Synonym Symbols
SYBL1; TIVAMP; VAMP-7; TI-VAMP
  [Similar Products]
NCBI Protein Information
vesicle-associated membrane protein 7
UniProt Protein Name
Vesicle-associated membrane protein 7
UniProt Synonym Protein Names
Synaptobrevin-like protein 1; Tetanus-insensitive VAMP; Ti-VAMP
UniProt Gene Name
VAMP7  [Similar Products]
UniProt Synonym Gene Names
SYBL1; VAMP-7; Ti-VAMP  [Similar Products]
UniProt Entry Name
VAMP7_HUMAN
NCBI Summary for VAMP7
This gene encodes a transmembrane protein that is a member of the soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) family. The encoded protein localizes to late endosomes and lysosomes and is involved in the fusion of transport vesicles to their target membranes. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Jun 2010]
UniProt Comments for VAMP7
VAMP7: Involved in the targeting and/or fusion of transport vesicles to their target membrane during transport of proteins from the early endosome to the lysosome. Required for heterotypic fusion of late endosomes with lysosomes and homotypic lysosomal fusion. Required for calcium regulated lysosomal exocytosis. Involved in the export of chylomicrons from the endoplasmic reticulum to the cis Golgi. Required for exocytosis of mediators during eosinophil and neutrophil degranulation, and target cell killing by natural killer cells. Required for focal exocytosis of late endocytic vesicles during phagosome formation. Belongs to the synaptobrevin family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: Xq28 and Yq12

Cellular Component: apical part of cell; cell junction; cell surface; cytoplasm; endoplasmic reticulum membrane; integral to membrane; intracellular membrane-bound organelle; lamellipodium; late endosome membrane; lysosomal membrane; membrane; neuron projection; perinuclear region of cytoplasm; phagocytic vesicle; phagocytic vesicle membrane; plasma membrane; pseudopodium; secretory granule; secretory granule membrane; SNARE complex; synapse; trans-Golgi network

Molecular Function: protein binding; SNAP receptor activity; SNARE binding; syntaxin binding

Biological Process: calcium ion-dependent exocytosis; endosome to lysosome transport; eosinophil degranulation; ER to Golgi vesicle-mediated transport; Golgi to plasma membrane protein transport; natural killer cell degranulation; neutrophil degranulation; phagocytosis, engulfment; positive regulation of dendrite morphogenesis; post-Golgi vesicle-mediated transport; triacylglycerol transport; vesicle fusion; vesicle fusion with Golgi apparatus; vesicle transport along microtubule; vesicle-mediated transport
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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