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anti-VNN1 antibody :: Rabbit anti-Human VNN1 Polyclonal Antibody

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Catalog # MBS2528597
Unit / Price
  0.02 mL  /  $110 +1 FREE 8GB USB
  0.06 mL  /  $150 +1 FREE 8GB USB
  0.12 mL  /  $225 +1 FREE 8GB USB
  0.2 mL  /  $360 +1 FREE 8GB USB
Immunofluorescence (IF)
Product Name

VNN1, Polyclonal Antibody

Popular Item
Full Product Name

VNN1 Polyclonal Antibody

Product Synonym Names
HDLCQ8; Tiff66
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
MBS2528597 Technical Datasheet
OMIM
603570
3D Structure
ModBase 3D Structure for O95497
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Purity/Purification
Affinity purification
Immunogen
Synthetic peptide of human VNN1
Buffer
PBS with 0.05% sodium azide, 50% glycerol, pH7.3
Preparation and Storage
Store at -20 degree C. Avoid freeze / thaw cycles.
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of anti-VNN1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-VNN1 antibody
This gene encodes a member of the vanin family of proteins, which share extensive sequence similarity with each other, and also with biotinidase. The family includes secreted and membrane-associated proteins, a few of which have been reported to participate in hematopoietic cell trafficking. No biotinidase activity has been demonstrated for any of the vanin proteins, however, they possess pantetheinase activity, which may play a role in oxidative-stress response. This protein, like its mouse homolog, is likely a GPI-anchored cell surface molecule. The mouse protein is expressed by the perivascular thymic stromal cells and regulates migration of T-cell progenitors to the thymus. This gene lies in close proximity to, and in the same transcriptional orientation as, two other vanin genes on chromosome 6q23-q24.
Applications Tested/Suitable for anti-VNN1 antibody
ELISA (EIA), Immunofluorescence (IF)
Application Notes for anti-VNN1 antibody
IHC: 1:50-100
IF/ICC: 1:100-1:500

Immunofluorescence (IF) of anti-VNN1 antibody
Immunofluorescence of HepG2 cell using VNN1 Polyclonal Antibody at dilution of 1:100.
anti-VNN1 antibody Immunofluorescence (IF) image
NCBI/Uniprot data below describe general gene information for VNN1. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
57,012 Da
NCBI Official Full Name
VNN1 protein
NCBI Official Synonym Full Names
vanin 1
NCBI Official Symbol
NCBI Official Synonym Symbols
HDLCQ8; Tiff66
  [Similar Products]
NCBI Protein Information
pantetheinase; pantetheine hydrolase; vanin-1; vannin 1; vascular non-inflammatory molecule 1
UniProt Protein Name
Pantetheinase
UniProt Synonym Protein Names
Pantetheine hydrolase; Tiff66; Vascular non-inflammatory molecule 1; Vanin-1
Protein Family
UniProt Gene Name
UniProt Synonym Gene Names
Vanin-1  [Similar Products]
UniProt Entry Name
VNN1_HUMAN
NCBI Summary for VNN1
This gene encodes a member of the vanin family of proteins, which share extensive sequence similarity with each other, and also with biotinidase. The family includes secreted and membrane-associated proteins, a few of which have been reported to participate in hematopoietic cell trafficking. No biotinidase activity has been demonstrated for any of the vanin proteins, however, they possess pantetheinase activity, which may play a role in oxidative-stress response. This protein, like its mouse homolog, is likely a GPI-anchored cell surface molecule. The mouse protein is expressed by the perivascular thymic stromal cells and regulates migration of T-cell progenitors to the thymus. This gene lies in close proximity to, and in the same transcriptional orientation as, two other vanin genes on chromosome 6q23-q24. [provided by RefSeq, Feb 2009]
UniProt Comments for VNN1
VNN1: Amidohydrolase that hydrolyzes specifically one of the carboamide linkages in D-pantetheine thus recycling pantothenic acid (vitamin B5) and releasing cysteamine. Belongs to the CN hydrolase family. BTD/VNN subfamily.

Protein type: Membrane protein, GPI anchor; Membrane protein, integral; EC 3.5.1.92; Cell adhesion; Cofactor and Vitamin Metabolism - pantothenate and CoA biosynthesis; Motility/polarity/chemotaxis; Hydrolase

Chromosomal Location of Human Ortholog: 6q23-q24

Cellular Component: plasma membrane; integral to membrane

Molecular Function: pantetheine hydrolase activity

Biological Process: positive regulation of T cell differentiation in the thymus; cell-cell adhesion; chronic inflammatory response; pantothenate metabolic process; innate immune response; response to oxidative stress; inflammatory response; cell motility; acute inflammatory response
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Products associated withanti-VNN1 antibody
 Reference Product  PubMed Publications
 SRY antibody  >1 publications with VNN1 and SRY
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